Comparison · NCT04455815-916facd3
Camostat vs Control Arm: Number of Community Patients Admitted to Hospital Due to COVID-19
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Camostat vs Control Arm: Number of Community Patients Admitted to Hospital Due to COVID-19. Trial comparisons, record NCT04455815-916facd3. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04455815-916facd3
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.143 | 0.0401 | 0.399 | wilson | |
| Risk in group 2 | 0.167 | 0.0584 | 0.392 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0238 | -0.272 | 0.255 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.857 | 0.165 | 4.45 | log | |
| Odds ratio, group 1 over group 2 | 0.833 | 0.119 | 5.82 | log | |
| Number needed to treat, for one fewer participant with the outcome on Camostat than on Control Arm | 42 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: control.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Camostat | Patient to receive treatment with camostat tablets, 200mg four times daily (qds) for 14 days.~Camostat: Patient to receive treatment with camostat tablets, 200mg four times daily (qds) for 14 days. | 2 | 14 | OG000 |
| Group 2 | Control Arm | Patient to receive best supportive care. | 3 | 18 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Community Patients Admitted to Hospital Due to COVID-19
- Description
- Number of patients who were recruited in community healthcare settings who were subsequently admitted to hospital due to COVID-19.
- Time frame
- Days 1 - 28
- Population
Treatment arm patients who received camostat for a minimum of five days, and control arm patients who completed up to Day 14 or came off trial at an earlier timepoint due to an endpoint (e.g. hospitalisation).
Source ClinicalTrials.gov
Trial
- Title
- A Trial Looking at the Use of Camostat in People Who Have Tested Positive for Coronavirus (COVID-19) (SPIKE-1)
- NCT number
- NCT04455815
- Phases
- PHASE2
- Conditions
- COVID-19 Infection
- Interventions
- Camostat
- Lead sponsor
- Cancer Research UK
- Results first posted
- 2023-12-11
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04455815?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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