Comparison · NCT04489771-deaths
Belzutifan 200 mg vs Belzutifan 120 mg: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Belzutifan 200 mg vs Belzutifan 120 mg: deaths from any cause. Trial comparisons, record NCT04489771-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04489771-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.359 | 0.261 | 0.47 | wilson | |
| Risk in group 2 | 0.329 | 0.234 | 0.441 | wilson | |
| Risk difference, group 1 minus group 2 | 0.03 | -0.118 | 0.176 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.09 | 0.705 | 1.69 | log | |
| Odds ratio, group 1 over group 2 | 1.14 | 0.587 | 2.22 | log | |
| Number needed to harm, for one more death from any cause on Belzutifan 200 mg than on Belzutifan 120 mg | 33.3 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Belzutifan 200 mg | Participants received 200 mg of belzutifan by oral administration, QD, until disease progression or discontinuation. | 28 | 78 | EG000 |
| Group 2 | Belzutifan 120 mg | Participants received 120 mg of belzutifan by oral administration, QD, until disease progression or discontinuation. | 25 | 76 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Up to approximately 27 months
Source ClinicalTrials.gov
Trial
- Title
- A Study of Belzutifan (MK-6482) in Participants With Advanced Renal Cell Carcinoma (MK-6482-013)
- NCT number
- NCT04489771
- Phases
- PHASE2
- Conditions
- Carcinoma, Renal Cell
- Interventions
- Belzutifan
- Lead sponsor
- Merck Sharp & Dohme LLC
- Results first posted
- 2024-02-28
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04489771?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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