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Comparison · NCT04615624-ed6d67f5

Furosemide vs Placebo: Induction of Labor

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Furosemide vs Placebo: Induction of Labor. Trial comparisons, record NCT04615624-ed6d67f5. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04615624-ed6d67f5

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.2120.1070.378wilson
Risk in group 20.1250.04970.281wilson
Risk difference, group 1 minus group 20.0871-0.1010.269newcombe hybrid score
Risk ratio, group 1 over group 21.70.5495.24log
Odds ratio, group 1 over group 21.880.4947.19log
Number needed to treat, for one more participant with the outcome on Furosemide than on Placebo11.5from the risk difference intervalthe interval includes no difference

Groups2

Group 2 names the comparator: placebo.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Furosemide
When patient meets inclusion criteria and is randomized to treatment drug, she receives 40mg /4 milliliters (mL) IV furosemide in addition to usual antihypertensive.~Furosemide: Furosemide, a loop diuretic
733OG000
Group 2PlaceboWhen patient meets inclusion criteria and is randomized to placebo, she receives one dose of 4mL normal saline in addition to usual antihypertensive.~Placebo: Normal saline432OG001

Outcome

Type
OTHER_PRE_SPECIFIED
Title
Induction of Labor
Description
Number of women who required induction of labor
Time frame
at the time of induction of labor
Population

Source ClinicalTrials.gov

Trial

Title
Furosemide vs. Placebo for Severe Antepartum Hypertension
NCT number
NCT04615624
Phases
PHASE3
Conditions
Pre-Eclampsia, Hypertension in Pregnancy, Pregnancy Complications, Hypertension, Pregnancy-Induced
Interventions
Furosemide, Placebo
Lead sponsor
Melanie Maykin, MD
Results first posted
2024-04-18

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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