Comparison · NCT04625283-99012d35
Ketamine vs Saline: Number of Participants With Ileus
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Ketamine vs Saline: Number of Participants With Ileus. Trial comparisons, record NCT04625283-99012d35. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04625283-99012d35
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0922 | 0.0737 | 0.115 | wilson | |
| Risk in group 2 | 0.0492 | 0.0359 | 0.0671 | wilson | |
| Risk difference, group 1 minus group 2 | 0.043 | 0.0173 | 0.0691 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.87 | 1.28 | 2.75 | log | |
| Odds ratio, group 1 over group 2 | 1.96 | 1.3 | 2.96 | log | |
| Number needed to treat, for one more participant with the outcome on Ketamine than on Saline | 23.3 | 14.5 | 57.8 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Ketamine | Participants in this arm will receive intraoperative ketamine bolus (0.5mg/kg) followed by continuous infusion 5 mcg/kg/min and also will receive postoperative ketamine infusion (2.5 mcg/kg/min, up to 100kg max) for 48 hours.~Ketamine: Participants in the ketamine arm will receive intraoperative and postoperative ketamine. | 71 | 770 | OG000 |
| Group 2 | Saline | Participants in this arm will receive an equivalent volume of intraoperative saline bolus followed by continuous saline infusion and also will receive postoperative saline infusion for 48 hours.~Placebo: Participants in the placebo arm will receive intraoperative and postoperative saline. | 37 | 752 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Ileus
- Description
- Number of participants reporting ileus requiring gastric decompression as defined by orogastric or nasogastric tube placement in the postoperative period.
- Time frame
- From hospital admission until discharge, typically 3-5 days
- Population
Source ClinicalTrials.gov
Trial
- Title
- The Impact of Perioperative Ketamine Infusion on Surgical Recovery
- NCT number
- NCT04625283
- Phases
- PHASE4
- Conditions
- Opioid Use, Enhanced Recovery After Surgery, Anesthesia, Ketamine, Pain, Postoperative
- Interventions
- Ketamine, Placebo
- Lead sponsor
- Vanderbilt University Medical Center
- Results first posted
- 2025-02-04
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04625283?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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