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Comparison · NCT04703075-deaths

Arm A: 1HP vs Arm B: 3HP: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Arm A: 1HP vs Arm B: 3HP: deaths from any cause. Trial comparisons, record NCT04703075-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04703075-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 100.0000000000000000008670.0152wilson
Risk in group 200.0000000000000000008670.0151wilson
Risk difference, group 1 minus group 20-0.01510.0152newcombe hybrid score
Risk ratio, group 1 over group 2loga group has no participants with the outcome
Odds ratio, group 1 over group 2loga cell of the two-by-two table is zero
Number needed to harmfrom the risk difference intervalthe two groups' risks are equal

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Arm A: 1HPParticipants will receive Rifapentine 600 mg daily and isoniazid (INH) 300 mg daily for 4 weeks.~Rifapentine 600 mg and INH 300 mg: Participants will receive Rifapentine 600 mg and INH 300 mg0249EG000
Group 2Arm B: 3HPParticipants will receive Rifapentine 900 mg and isoniazid 900 mg weekly for 12 weeks.~Rifapentine 900 mg and INH 900 mg: Participants will receive Rifapentine 900 mg and INH 900mg0251EG001

Harm

What it counts
Total, all-cause mortality
Time frame
Up to 6 months

Source ClinicalTrials.gov

Trial

Title
Ultra Curto (Ultra Short) TB Prevention Therapy
NCT number
NCT04703075
Phases
PHASE4
Conditions
Tuberculosis
Interventions
Rifapentine 600 mg and INH 300 mg, Rifapentine 900 mg and INH 900 mg
Lead sponsor
Johns Hopkins University
Results first posted
2025-06-19

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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