Comparison · NCT04704050-bb4f26a1
Treatment Group vs Control Group: Post-ablation Atrial Fibrillation Recurrence Documented by an AAD Initiation
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Treatment Group vs Control Group: Post-ablation Atrial Fibrillation Recurrence Documented by an AAD Initiation. Trial comparisons, record NCT04704050-bb4f26a1. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04704050-bb4f26a1
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0833 | 0.0149 | 0.354 | wilson | |
| Risk in group 2 | 0.2 | 0.0567 | 0.51 | wilson | |
| Risk difference, group 1 minus group 2 | -0.117 | -0.434 | 0.189 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.417 | 0.044 | 3.95 | log | |
| Odds ratio, group 1 over group 2 | 0.364 | 0.0279 | 4.74 | log | |
| Number needed to treat, for one fewer participant with the outcome on Treatment Group than on Control Group | 8.57 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: control.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Treatment Group | Dronedarone 400 mg orally, twice per day (BID)~dronedarone 400 mg Oral Tablet: Dronedarone is an anti-arrhythmic drug with properties belonging to Vaughan-Williams class I-IV.~Participants will receive dronedarone 400 mg tablet, to be taken orally and twice daily for 52 weeks. | 1 | 12 | OG000 |
| Group 2 | Control Group | Placebo tablet orally, twice per day (BID)~Placebo: Participants will receive a placebo tablet matching the physical appearance of dronedarone, to be taken orally and twice daily for 52 weeks. | 2 | 10 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Post-ablation Atrial Fibrillation Recurrence Documented by an AAD Initiation
- Description
- New anti-arrhythmic drug (AAD) initiation for AF recurrence after AF ablation, including initiation of the treatment during the blanking period, or with no available positive ECG reading.
- Time frame
- Up to 56 weeks. From date of ablation until the date of first documented Atrial Fibrillation recurrence, whichever came first, assessed up to 56 weeks.
- Population
Source ClinicalTrials.gov
Trial
- Title
- Effect of Dronedarone on Atrial Fibrosis Progression and Atrial Fibrillation Recurrence
- NCT number
- NCT04704050
- Phases
- PHASE4
- Conditions
- Atrial Fibrillation, Atrial Fibrillation Recurrent
- Interventions
- dronedarone 400 mg Oral Tablet, Placebo
- Lead sponsor
- Tulane University School of Medicine
- Results first posted
- 2025-10-16
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04704050?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT04704050-bb4f26a1