Comparison · NCT04756804-sae
70% Isopropyl Alcohol Novel Preoperative Skin Antiseptic vs 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol Preoperative Skin Antiseptic: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. 70% Isopropyl Alcohol Novel Preoperative Skin Antiseptic vs 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol Preoperative Skin Antiseptic: serious adverse events. Trial comparisons, record NCT04756804-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04756804-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.4 | 0.234 | 0.593 | wilson | |
| Risk in group 2 | 0.423 | 0.255 | 0.611 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0231 | -0.273 | 0.232 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.945 | 0.49 | 1.82 | log | |
| Odds ratio, group 1 over group 2 | 0.909 | 0.298 | 2.78 | log | |
Number needed to treat, for one fewer participant with a serious adverse event on 70% Isopropyl Alcohol Novel Preoperative Skin Antiseptic than on 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol Preoperative Skin Antiseptic | 43.3 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | 70% Isopropyl Alcohol Novel Preoperative Skin Antiseptic | 70% v/v Isopropyl Alcohol novel preoperative skin antisepsis preparation~70% v/v Isopropyl Alcohol Surgical Solution: Patient preoperative skin preparation | 10 | 25 | EG000 |
| Group 2 | 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol Preoperative Skin Antiseptic | 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol preoperative skin antisepsis preparation~2%w/v Chlorhexidine Gluconate / 70% v/v Isopropyl Alcohol: Patient preoperative skin preparation | 11 | 26 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- AE's reported from time of enrollment through follow up (30 days post op), up to 51 days ( up to 21 days for screening).
Source ClinicalTrials.gov
Trial
- Title
- Perioperative Patient Skin Antiseptic Preparation Evaluation
- NCT number
- NCT04756804
- Phases
- PHASE3
- Conditions
- Surgical Site Infection
- Interventions
- 70% v/v Isopropyl Alcohol Surgical Solution, 2%w/v Chlorhexidine Gluconate / 70% v/v Isopropyl Alcohol
- Lead sponsor
- Zurex Pharma, Inc.
- Results first posted
- 2024-03-20
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04756804?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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