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Comparison · NCT04790279-02c22d45

Amlodipine vs Nifedipine ER: Number of Patients Discontinuing Medication Due to Side Effects

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Amlodipine vs Nifedipine ER: Number of Patients Discontinuing Medication Due to Side Effects. Trial comparisons, record NCT04790279-02c22d45. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04790279-02c22d45

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 1000.07wilson
Risk in group 20.1010.050.195wilson
Risk difference, group 1 minus group 2-0.101-0.195-0.0145newcombe hybrid score
Risk ratio, group 1 over group 2loga group has no participants with the outcome
Odds ratio, group 1 over group 2loga cell of the two-by-two table is zero
Number needed to treat, for one fewer participant with the outcome on Amlodipine than on Nifedipine ER9.865.1368.7from the risk difference interval

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1AmlodipineAmlodipine Per Protocol051OG000
Group 2Nifedipine ERNifedipine ER Per Protocol769OG001

Outcome

Type
SECONDARY
Title
Number of Patients Discontinuing Medication Due to Side Effects
Description
Time frame
Through hospital stay, on average 2-5 days
Population

Source ClinicalTrials.gov

Trial

Title
Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension
NCT number
NCT04790279
Phases
PHASE4
Conditions
Hypertension in Pregnancy
Interventions
Amlodipine, NIFEdipine ER
Lead sponsor
Prisma Health-Upstate
Results first posted
2024-10-28

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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