Comparison · NCT04860518-c8bcd111
IV IFN Beta-1a vs IV Dexamethasone: In-hospital Mortality at Day 28 and Day 90
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. IV IFN Beta-1a vs IV Dexamethasone: In-hospital Mortality at Day 28 and Day 90. Trial comparisons, record NCT04860518-c8bcd111. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04860518-c8bcd111
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0 | 0 | 0.658 | wilson | |
| Risk in group 2 | 0 | 0.0000000000000000555 | 0.561 | wilson | |
| Risk difference, group 1 minus group 2 | 0 | -0.561 | 0.658 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | log | a group has no participants with the outcome | |||
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to treat | from the risk difference interval | the two groups' risks are equal |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | IV IFN Beta-1a | Patients receiving active drug: will receive two separate bolus injections one containing IFN-beta -1a and another injection containing Saline.~IFN beta-1a: Treated daily with IFN beta-1a 10 μg as an IV bolus for 6 days while hospitalised | 0 | 2 | OG000 |
| Group 2 | IV Dexamethasone | Patients receiving active comparator: will receive two separate bolus injections one containing saline and another injection containing Dexamethasone.~Dexamethasone: Treated daily with dexamethasone as an IV bolus for 6 days while hospitalised | 0 | 3 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- In-hospital Mortality at Day 28 and Day 90
- Description
- Percentage of participants per study group that die when in still hospital at Day 28 or Day 90 of the trial
- Time frame
- Day 28 and Day 90
- Population
Source ClinicalTrials.gov
Trial
- Title
- Human Intravenous Interferon Beta-Ia Safety and Preliminary Efficacy in Hospitalized Subjects With COVID-19
- NCT number
- NCT04860518
- Phases
- PHASE2
- Conditions
- Covid19
- Interventions
- IFN beta-1a, Dexamethasone
- Lead sponsor
- Faron Pharmaceuticals Ltd
- Results first posted
- 2022-10-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04860518?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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