Comparison · NCT04865289-deaths
Lenvatinib + Pembrolizumab vs Paclitaxel + Carboplatin: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Lenvatinib + Pembrolizumab vs Paclitaxel + Carboplatin: deaths from any cause. Trial comparisons, record NCT04865289-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04865289-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.459 | 0.351 | 0.572 | wilson | |
| Risk in group 2 | 0.446 | 0.324 | 0.576 | wilson | |
| Risk difference, group 1 minus group 2 | 0.013 | -0.156 | 0.18 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.03 | 0.702 | 1.51 | log | |
| Odds ratio, group 1 over group 2 | 1.05 | 0.525 | 2.12 | log | |
| Number needed to harm, for one more death from any cause on Lenvatinib + Pembrolizumab than on Paclitaxel + Carboplatin | 76.7 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Lenvatinib + Pembrolizumab | Participants received lenvatinib daily and pembrolizumab once at the start of each 3-week treatment cycle. | 34 | 74 | EG000 |
| Group 2 | Paclitaxel + Carboplatin | Participants received paclitaxel and carboplatin once at the start of each 3-week treatment cycle. | 25 | 56 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- From randomization to the date of death or last participant data collection (up to approximately 61 months).
Source ClinicalTrials.gov
Trial
- Title
- Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Versus Chemotherapy for Endometrial Carcinoma (ENGOT-en9 / MK-7902-001) - China Extension Study
- NCT number
- NCT04865289
- Phases
- PHASE3
- Conditions
- Endometrial Neoplasms
- Interventions
- Lenvatinib, Pembrolizumab, Paclitaxel, Carboplatin
- Lead sponsor
- Merck Sharp & Dohme LLC
- Results first posted
- 2024-10-18
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04865289?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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