Comparison · NCT04908189-d4ed6df1
Deucravacitinib vs Placebo: Number of Participants Meeting Achievement of Minimal Disease Activity (MDA) at Week 16
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Deucravacitinib vs Placebo: Number of Participants Meeting Achievement of Minimal Disease Activity (MDA) at Week 16. Trial comparisons, record NCT04908189-d4ed6df1. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04908189-d4ed6df1
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.256 | 0.211 | 0.308 | wilson | |
| Risk in group 2 | 0.147 | 0.112 | 0.191 | wilson | |
| Risk difference, group 1 minus group 2 | 0.109 | 0.0461 | 0.171 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.74 | 1.25 | 2.41 | log | |
| Odds ratio, group 1 over group 2 | 1.99 | 1.33 | 2.98 | log | |
| Number needed to treat, for one more participant with the outcome on Deucravacitinib than on Placebo | 9.18 | 5.85 | 21.7 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Deucravacitinib | Deucravacitinib 6 mg daily | 80 | 312 | OG000 |
| Group 2 | Placebo | Placebo daily | 46 | 312 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants Meeting Achievement of Minimal Disease Activity (MDA) at Week 16
- Description
Number participants meeting achievement of MDA where an MDA response is achievement of 5 of 7 following outcomes at Week 16:~1. Tender joint count ≤ 1~2. Swollen joint count ≤ 1~3. Psoriasis Area and Severity Index (PASI) ≤ 1 or body surface area (BSA) ≤ 3%~4. Patient assessment of psoriatic arthiritis (PsA) pain ≤ 15~5. Patient Global Assessment of PsA disease activity ≤ 20~6. HAQ-DI ≤ 0.5~7. Tender enthesial points ≤ 1
- Time frame
- Week 16
- Population
- All randomized participants of deucravacitinib and placebo as pre-specified in protocol
Source ClinicalTrials.gov
Trial
- Title
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment
- NCT number
- NCT04908189
- Phases
- PHASE3
- Conditions
- Psoriatic Arthritis
- Interventions
- Deucravacitinib, Placebo, Apremilast
- Lead sponsor
- Bristol-Myers Squibb
- Results first posted
- 2025-04-13
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04908189?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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