Cases vs Controls (reference group): Risk of Recurrent Depressive Disorder Within Adult Patients With Vitilgo
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.0184 | 0.0154 | 0.0221 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.0148 | 0.0132 | 0.0165 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.00364 | 0.000112 | 0.00763 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.25 | 1.01 | 1.54 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.25 | 1.01 | 1.55 | log | ClinicalTrials.gov | |
| Number needed to treat, for one more participant with the outcome on Cases than on Controls (reference group) | 275 | 131 | 8,910 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Cases | Patients with a confirmed diagnosis of Vitiligo within the study period will be included as cases for analysis. | 113 | 6,131 | OG000 | ClinicalTrials.gov |
| Group 2 | Controls (reference group) | The controls will be defined by matching cases with people who have never been diagnosed with vitiligo either prior to or during the study period, by age and sex, at General Practice level. | 312 | 21,091 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | PRIMARY | ClinicalTrials.gov |
| Title | Risk of Recurrent Depressive Disorder Within Adult Patients With Vitilgo | ClinicalTrials.gov |
| Description | Adjusted hazard ratio calculated using Cox proportional hazards models. Adjusted for age, gender, ethnicity, social deprivation quintile, body mass index, smoking status, alcohol use and comorbidities (hypertension, hyperlipidaemia, type 2 diabetes, atrial fibrillation, angina, myocardial infarction, heart failure, stroke, chronic kidney disease stages 3-5, chronic obstructive pulmonary disease, asthma, chronic liver disease and dementia). | ClinicalTrials.gov |
| Time frame | Within two years of vitiligo diagnosis. For matched controls, within two years of the date of diagnosis of their matched case. | ClinicalTrials.gov |
| Population | Patients with a pre-existing diagnosis of recurrent depressive disorder were excluded from the analysis | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Mental Health Associations With Vitiligo | ClinicalTrials.gov |
| NCT number | NCT04953338 | ClinicalTrials.gov |
| Phases | ClinicalTrials.gov | |
| Conditions | Vitiligo, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders, Social Phobia, Adjustment Disorders, Substance Abuse, Self-Harm, Deliberate, Overdose, Suicide, Attempted, Parasuicide | ClinicalTrials.gov |
| Interventions | Exposure of mental health condtion of interest | ClinicalTrials.gov |
| Lead sponsor | Momentum Data | ClinicalTrials.gov |
| Results first posted | 2025-12-02 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT04953338?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.