Cases vs Controls: Prevalence of Squamous Cell Carcinoma Skin Cancer in Adult People Diagnosed With Vitiligo
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.00204 | 0.00119 | 0.00349 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.00283 | 0.00225 | 0.00356 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.000786 | -0.00191 | 0.000776 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.722 | 0.4 | 1.3 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.722 | 0.4 | 1.3 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer participant with the outcome on Cases than on Controls | 1,270 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Cases | Patients with a confirmed diagnosis of Vitiligo within the study period will be included as cases for analysis.~Exposure of skin cancer of interest: Melanoma and nonmelanoma skin cancers: squamous cell carcinoma, basal cell carcinoma and actinic keratoses. | 13 | 6,360 | OG000 | ClinicalTrials.gov |
| Group 2 | Controls | The controls will be defined by matching cases with people who have never been diagnosed with vitiligo either prior to or during the study period, by age and sex, at General Practice level.~Exposure of skin cancer of interest: Melanoma and nonmelanoma skin cancers: squamous cell carcinoma, basal cell carcinoma and actinic keratoses. | 72 | 25,439 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | SECONDARY | ClinicalTrials.gov |
| Title | Prevalence of Squamous Cell Carcinoma Skin Cancer in Adult People Diagnosed With Vitiligo | ClinicalTrials.gov |
| Description | Prevalence of squamous cell carcinoma skin cancer in adult people diagnosed with vitiligo at or before recruitment | ClinicalTrials.gov |
| Time frame | At index date. | ClinicalTrials.gov |
| Population | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo | ClinicalTrials.gov |
| NCT number | NCT04969419 | ClinicalTrials.gov |
| Phases | ClinicalTrials.gov | |
| Conditions | Vitiligo, Melanoma (Skin), Nonmelanoma Skin Cancer, Squamous Cell Carcinoma, Basal Cell Carcinoma, Actinic Keratoses | ClinicalTrials.gov |
| Interventions | Exposure of skin cancer of interest | ClinicalTrials.gov |
| Lead sponsor | Momentum Data | ClinicalTrials.gov |
| Results first posted | 2025-01-14 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT04969419?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.