Intervention Arm vs Control Arm: COVID-19 Vaccination Within 3 Months

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

Measures 6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

Measure	Value	95% interval, lower	95% interval, upper	Method	Source
Risk in group 1	0.0125	0.0105	0.0147	wilson	ClinicalTrials.gov
Risk in group 2	0.00903	0.00742	0.011	wilson	ClinicalTrials.gov
Risk difference, group 1 minus group 2	0.00343	0.000687	0.00619	newcombe hybrid score	ClinicalTrials.gov
Risk ratio, group 1 over group 2	1.38	1.07	1.78	log	ClinicalTrials.gov
Odds ratio, group 1 over group 2	1.38	1.07	1.8	log	ClinicalTrials.gov
Number needed to treat, for one more participant with the outcome on Intervention Arm than on Control Arm	292	161	1,460	from the risk difference interval	ClinicalTrials.gov

Groups 2

Group 2 names the comparator: control.

Group	Title	Description	With the outcome	Analysed	ClinicalTrials.gov code	Source
Group 1	Intervention Arm	Primary care text message outreach to unvaccinated patients and resources to support PCPs~Primary care text message outreach to unvaccinated patients and resources to support PCPs: Patients: Eligible patients will receive a series of text messages from their PCP or primary care clinic recommending a study website as a trusted source of information about the COVID-19 vaccines and information on how and where to schedule a vaccination.~Providers: PCPs will receive resources to support their conversations with patients about the COVID-19 vaccines (factsheets, prescription pads, electronic smartphrase).	137	10,996	OG000	ClinicalTrials.gov
Group 2	Control Arm	Patients will receive usual care	98	10,848	OG001	ClinicalTrials.gov

Outcome 5

Field	Value	Source
Type	PRIMARY	ClinicalTrials.gov
Title	COVID-19 Vaccination Within 3 Months	ClinicalTrials.gov
Description	The number of patients in the intervention and control arms who receive at least one dose of a COVID-19 vaccination within 3 months of the last text message being sent will be ascertained via the Electronic Health Record (EHR).	ClinicalTrials.gov
Time frame	3 months	ClinicalTrials.gov
Population	Intention to treat population	ClinicalTrials.gov

Trial 8

Field	Value	Source
Title	Trusted Messengers: Intervention to Promote COVID-19 Vaccination	ClinicalTrials.gov
NCT number	NCT04981392	ClinicalTrials.gov
Phases	NA	ClinicalTrials.gov
Conditions	Covid19, Vaccination	ClinicalTrials.gov
Interventions	Primary care text message outreach to unvaccinated patients and resources to support PCPs	ClinicalTrials.gov
Lead sponsor	University of Massachusetts, Worcester	ClinicalTrials.gov
Results first posted	2024-11-26	ClinicalTrials.gov
Results on ClinicalTrials.gov	https://clinicaltrials.gov/study/NCT04981392?tab=results	ClinicalTrials.gov

Source 4

Field	Value	Source
Release	trial-comparisons-2026-03-23-0.1.0	ClinicalTrials.gov
Release manifest SHA-256	f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57	ClinicalTrials.gov
AACT copy	2026-03-23	ClinicalTrials.gov
Tables read	outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet	ClinicalTrials.gov

The same record as JSON

Release trial-comparisons-2026-03-23-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.