Comparison · NCT05049616-73598be6
Hctz/Lisinopril vs Extended release nifedipine: Number of Participants With Stage 2 Hypertension
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Hctz/Lisinopril vs Extended release nifedipine: Number of Participants With Stage 2 Hypertension. Trial comparisons, record NCT05049616-73598be6. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT05049616-73598be6
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.267 | 0.142 | 0.444 | wilson | |
| Risk in group 2 | 0.429 | 0.265 | 0.609 | wilson | |
| Risk difference, group 1 minus group 2 | -0.162 | -0.382 | 0.0796 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.622 | 0.299 | 1.29 | log | |
| Odds ratio, group 1 over group 2 | 0.485 | 0.161 | 1.46 | log | |
| Number needed to treat, for one fewer participant with the outcome on Hctz/Lisinopril than on Extended release nifedipine | 6.18 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Hctz/Lisinopril | Hctz/Lisinopril for postpartum management of hypertension. either a combined pill of ACE inhibitors and diuretics (Hydrochlorothiazide/Lisinopril)~ACE Inhibitors and Diuretics: Hctz/Lisinopril (brand name: Zestoretic) | 8 | 30 | OG000 |
| Group 2 | Extended release nifedipine | calcium channel blocker (Nifedipine~NIFEdipine ER: Extended release nifedipine | 12 | 28 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Number of Participants With Stage 2 Hypertension
- Description
Stage 2 hypertension at day 7-10 after delivery (defined as SBP ≥ 140 and/or DBP ≥ 90 mmHg) or admission to the hospital for blood pressure control prior to day 10.~Primary outcome will be calculated as the average BP reading for day 7-10 after delivery.
- Time frame
- 7-10 after delivery
- Population
- Data were not collected for 1 participants in the Hctz/Lisionpril arm. Data were not collected for 8 participants in the extended release nifedipine arm.
Source ClinicalTrials.gov
Trial
- Title
- Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension
- NCT number
- NCT05049616
- Phases
- PHASE4
- Conditions
- Hypertension in Pregnancy, Postpartum Preeclampsia
- Interventions
- ACE Inhibitors and Diuretics, NIFEdipine ER
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Results first posted
- 2023-08-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT05049616?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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