Comparison · NCT05142722-deaths
Obicetrapib 10mg vs Placebo: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Obicetrapib 10mg vs Placebo: deaths from any cause. Trial comparisons, record NCT05142722-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT05142722-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0113 | 0.00723 | 0.0175 | wilson | |
| Risk in group 2 | 0.0142 | 0.00816 | 0.0247 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00296 | -0.0142 | 0.00577 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.792 | 0.386 | 1.62 | log | |
| Odds ratio, group 1 over group 2 | 0.79 | 0.382 | 1.63 | log | |
| Number needed to treat, for one fewer death from any cause on Obicetrapib 10mg than on Placebo | 338 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Obicetrapib 10mg | one 10mg obicetrapib tablet once daily~Obicetrapib: 10mg obicetrapib tablet | 19 | 1,685 | EG001 |
| Group 2 | Placebo | one placebo tablet once daily~Placebo: placebo tablet made to resemble active | 12 | 843 | EG000 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- From first dose of study drug up to Week 54
Source ClinicalTrials.gov
Trial
- Title
- Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies
- NCT number
- NCT05142722
- Phases
- PHASE3
- Conditions
- Dyslipidemias, High Cholesterol, Hypercholesterolemia, Familial Hypercholesterolemia, Atherosclerotic Cardiovascular Disease
- Interventions
- Placebo, Obicetrapib
- Lead sponsor
- NewAmsterdam Pharma
- Results first posted
- 2025-09-19
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT05142722?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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GET https://conductscience.org/api/comparisons/v1/NCT05142722-deaths