Comparison · NCT05167734-79ce83d7
Anemia Treatment Bundle vs Control (Standard of Care) Group: Number of Participants With Allogeneic Red Blood Cell Transfusions
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Anemia Treatment Bundle vs Control (Standard of Care) Group: Number of Participants With Allogeneic Red Blood Cell Transfusions. Trial comparisons, record NCT05167734-79ce83d7. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT05167734-79ce83d7
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0208 | 0.00369 | 0.109 | wilson | |
| Risk in group 2 | 0.118 | 0.0551 | 0.234 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0968 | -0.214 | 0.0113 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.177 | 0.0221 | 1.42 | log | |
| Odds ratio, group 1 over group 2 | 0.16 | 0.0185 | 1.38 | log | |
| Number needed to treat, for one fewer participant with the outcome on Anemia Treatment Bundle than on Control (Standard of Care) Group | 10.3 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: standard of care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Anemia Treatment Bundle | The intervention arm is multi-faceted with 3 primary components: 1) Optimized phlebotomy, defined by minimal volume draws and closed-loop blood sampling, all performed by a dedicated phlebotomy team independent from the treatment team; 2) Decision support aids, including visual and electronic alerts reminding the care team to minimize non-essential laboratory testing and mitigate patient-specific bleeding risk; and 3) Pharmacologic anemia treatment with a single dose of IV iron and/or subcutaneous erythropoietin (given immediately following enrollment) targeted to 2 broad groups: 1) anemias responsive to iron supplementation alone (i.e. acute blood loss, iron deficiency) and 2) anemias requiring erythropoietic stimulation (e.g. anemia of inflammation, anemia of renal disease).~Iron Dextran: 1000 mg IV~Erythropoietin (EPO): 40,000 units subcutaneous | 1 | 48 | OG001 |
| Group 2 | Control (Standard of Care) Group | Subjects received standard clinical care for the treatment of anemia while in the ICU. | 6 | 51 | OG000 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Allogeneic Red Blood Cell Transfusions
- Description
- Number (percentage) of patients transfused with allogeneic red blood cells
- Time frame
- 3-months post-hospitalization
- Population
- No data was collected or analyzed for 1 participant in the anemia treatment bundle arm.
Source ClinicalTrials.gov
Trial
- Title
- Practical Anemia Bundle for SusTained Blood Recovery
- NCT number
- NCT05167734
- Phases
- PHASE2
- Conditions
- Anemia, Critical Illness
- Interventions
- Iron Dextran, Erythropoietin (EPO)
- Lead sponsor
- Mayo Clinic
- Results first posted
- 2025-04-06
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT05167734?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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