IBD Cases vs Matched Controls (Reference Group): Stream 1: Relative Risk of Any Mental Health Condition
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.0874 | 0.0783 | 0.0973 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.0662 | 0.0619 | 0.0707 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.0212 | 0.0111 | 0.032 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.32 | 1.16 | 1.5 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.35 | 1.18 | 1.55 | log | ClinicalTrials.gov | |
| Number needed to treat, for one more participant with the outcome on IBD Cases than on Matched Controls (Reference Group) | 47.2 | 31.3 | 90.1 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | IBD Cases | All incident cases of Inflammatory Bowel Disease (IBD); comprising of Ulcerative Colitis, Crohn's Disease and IBD Unclassified in children, adolescents and young adults up to their 25th birthday. Cases will be defined based on an algorithm using diagnostic codes from the electronic medical record (EMR).~No specific intervention: Observational analysis of usual care only. | 299 | 3,423 | OG000 | ClinicalTrials.gov |
| Group 2 | Matched Controls (Reference Group) | People without a diagnosis in their electronic medical record (ERM) of Inflammatory Bowel Disease, matched on age group, sex, ethnicity (consistent with UK census categories: White, Asian, Black, Mixed, Other), index of multiple deprivation based on postcode, and by practice where numbers allow.~No specific intervention: Observational analysis of usual care only. | 811 | 12,256 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | PRIMARY | ClinicalTrials.gov |
| Title | Stream 1: Relative Risk of Any Mental Health Condition | ClinicalTrials.gov |
| Description | Calculated using Cox proportional hazards models using matched controls as the reference group. Adjusted for age, sex, socioeconomic status, ethnicity, and other common chronic childhood conditions. | ClinicalTrials.gov |
| Time frame | Retrospective data assessed from 2010-2020, up to 10 years | ClinicalTrials.gov |
| Population | Participants with a pre-existing diagnosis of mental health were excluded | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health | ClinicalTrials.gov |
| NCT number | NCT05206734 | ClinicalTrials.gov |
| Phases | ClinicalTrials.gov | |
| Conditions | Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder, Psychological Disorder, Self Harm, Suicide, Attempted, Parasuicide, Eating Disorders, Body Image Disorder, Attention Deficit Hyperactivity Disorder, Behavioral Disorder, Adjustment Disorders, Acute Stress Disorder, Schizophrenia, Bipolar Disorder, Post-traumatic Stress Disorder, Sleep Disturbance | ClinicalTrials.gov |
| Interventions | No specific intervention | ClinicalTrials.gov |
| Lead sponsor | Momentum Data | ClinicalTrials.gov |
| Results first posted | 2025-06-15 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT05206734?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.