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Comparison · NCT05481216-deaths

PLWHIV With COVID-19 Cases vs HIV Seronegative Patients With COVID-19 Controls: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. PLWHIV With COVID-19 Cases vs HIV Seronegative Patients With COVID-19 Controls: deaths from any cause. Trial comparisons, record NCT05481216-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT05481216-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.04940.03340.0724wilson
Risk in group 20.02080.01390.031wilson
Risk difference, group 1 minus group 20.02860.009620.0526newcombe hybrid score
Risk ratio, group 1 over group 22.371.354.17log
Odds ratio, group 1 over group 22.451.374.38log
Number needed to harm, for one more death from any cause on PLWHIV With COVID-19 Cases than on HIV Seronegative Patients With COVID-19 Controls3519104from the risk difference interval

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1PLWHIV With COVID-19 Cases
Patients who are at least 18 years of age with documented HIV-1 infection and confirmed SARS-CoV-2 infection by documented, or patient-reported, positive result on PCR testing of a nasopharyngeal or respiratory sample, before 1st April 2021.~COVID-19: Diagnosed with COVID-19 infection~HIV-1 infection: Diagnosed with HIV-1 infection
24486EG000
Group 2HIV Seronegative Patients With COVID-19 Controls
Patients at least 18 years of age with confirmed SARS-CoV-2 infection by documented, or patient-reported, positive result on PCR testing of a nasopharyngeal or respiratory sample, before 1st April 2021.~COVID-19: Diagnosed with COVID-19 infection
231,106EG001

Harm

What it counts
Total, all-cause mortality
Time frame
Baseline to week 6

Source ClinicalTrials.gov

Trial

Title
HIV-1 & Coronavirus-Coinfection in Europe: Morbidity & Risk Factors of COVID-19 in People Living With HIV
NCT number
NCT05481216
Phases
Conditions
HIV-1-infection, COVID-19
Interventions
COVID-19, HIV-1 infection
Lead sponsor
NEAT ID Foundation
Results first posted
2025-03-24

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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