Comparison · NCT05630885-sae
CVC Arm (Arm A) vs Placebo for CVC Arm (Arm B): serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. CVC Arm (Arm A) vs Placebo for CVC Arm (Arm B): serious adverse events. Trial comparisons, record NCT05630885-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT05630885-sae
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0541 | 0.0212 | 0.131 | wilson | |
| Risk in group 2 | 0.0556 | 0.0154 | 0.181 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0015 | -0.132 | 0.0852 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.973 | 0.187 | 5.07 | log | |
| Odds ratio, group 1 over group 2 | 0.971 | 0.169 | 5.57 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on CVC Arm (Arm A) than on Placebo for CVC Arm (Arm B) | 666 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | CVC Arm (Arm A) | Participants with pre-existing ART regimen of EFV took CVC 300 mg. Participants with all other pre-existing ART regimens took CVC 150 mg.~CVC 150 mg: Administered as one 150-mg tablet by mouth once a day with food.~CVC 300 mg: Administered as two 150-mg tablets by mouth once a day with food. | 4 | 74 | EG000 |
| Group 2 | Placebo for CVC Arm (Arm B) | Participants with pre-existing ART regimen of EFV took placebo for CVC 300 mg. Participants with all other pre-existing ART regimens took placebo for CVC 150 mg.~Placebo for CVC 150 mg: Administered as one 150-mg matching placebo tablets by mouth once a day with food.~Placebo for CVC 300 mg: Administered as two 150-mg matching placebo tablets by mouth once a day with food. | 2 | 36 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- From study entry to completion at Week 24 or premature study discontinuation.
Source ClinicalTrials.gov
Trial
- Title
- A Study to Evaluate the Effects of Cenicriviroc Mesylate on Arterial Inflammation in People Living With HIV
- NCT number
- NCT05630885
- Phases
- PHASE2
- Conditions
- HIV-1-infection, Elevated Cardiovascular Risk
- Interventions
- CVC 150 mg, CVC 300 mg, Placebo for CVC 150 mg, Placebo for CVC 300 mg
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- Results first posted
- 2025-07-16
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT05630885?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT05630885-sae