People With Alopecia Areata vs People Without Alopecia Areata (Reference Gropup): Likelihood of Recurrent Major Depressive Disorder

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

Measures 6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

Measure	Value	95% interval, lower	95% interval, upper	Method	Source
Risk in group 1	0.135	0.127	0.144	wilson	ClinicalTrials.gov
Risk in group 2	0.0916	0.0881	0.0953	wilson	ClinicalTrials.gov
Risk difference, group 1 minus group 2	0.0435	0.0344	0.0529	newcombe hybrid score	ClinicalTrials.gov
Risk ratio, group 1 over group 2	1.47	1.37	1.59	log	ClinicalTrials.gov
Odds ratio, group 1 over group 2	1.55	1.42	1.69	log	ClinicalTrials.gov
Number needed to treat, for one more participant with the outcome on People With Alopecia Areata than on People Without Alopecia Areata (Reference Gropup)	23	18.9	29.1	from the risk difference interval	ClinicalTrials.gov

Groups 2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

Group	Title	Description	With the outcome	Analysed	ClinicalTrials.gov code	Source
Group 1	People With Alopecia Areata	Children and adults aged 12+ with new onset Alopecia Areata registered with a contributing General practitioner (GP) practice during the study period.~No intervention: Observational analysis of usual care only.	835	6,183	OG000	ClinicalTrials.gov
Group 2	People Without Alopecia Areata (Reference Gropup)	Children and adults aged 12+ without Alopecia Areata registered with a contributing GP practice during the study period.~No intervention: Observational analysis of usual care only.	2,264	24,718	OG001	ClinicalTrials.gov

Outcome 5

Field	Value	Source
Type	PRIMARY	ClinicalTrials.gov
Title	Likelihood of Recurrent Major Depressive Disorder	ClinicalTrials.gov
Description	Estimated using logistic regression and reported using adjusted odds ratios	ClinicalTrials.gov
Time frame	Data was collected retrospectively, assessed prior to and up to two years following initial Alopecia Areata diagnosis for each participant	ClinicalTrials.gov
Population		ClinicalTrials.gov

Trial 8

Field	Value	Source
Title	Healthcare Disparities in Alopecia Areata	ClinicalTrials.gov
NCT number	NCT05727306	ClinicalTrials.gov
Phases		ClinicalTrials.gov
Conditions	Alopecia Areata	ClinicalTrials.gov
Interventions	No intervention	ClinicalTrials.gov
Lead sponsor	Momentum Data	ClinicalTrials.gov
Results first posted	2025-06-18	ClinicalTrials.gov
Results on ClinicalTrials.gov	https://clinicaltrials.gov/study/NCT05727306?tab=results	ClinicalTrials.gov

Source 4

Field	Value	Source
Release	trial-comparisons-2026-03-23-0.1.0	ClinicalTrials.gov
Release manifest SHA-256	f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57	ClinicalTrials.gov
AACT copy	2026-03-23	ClinicalTrials.gov
Tables read	outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet	ClinicalTrials.gov

The same record as JSON

Release trial-comparisons-2026-03-23-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.