Pre-Intervention: Patients Diagnosed With Conditions of Interest During Study Period vs Post-Intervention: Patients Diagnosed With Conditions of Interest During Study Period: Guideline-concordant Decision to Prescribe Antibiotics for Pediatric Acute Otitis Media
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.977 | 0.974 | 0.98 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.978 | 0.975 | 0.981 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.000625 | -0.00485 | 0.00366 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.999 | 0.995 | 1 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.972 | 0.802 | 1.18 | log | ClinicalTrials.gov | |
Number needed to treat, for one fewer participant with the outcome on Pre-Intervention: Patients Diagnosed With Conditions of Interest During Study Period than on Post-Intervention: Patients Diagnosed With Conditions of Interest During Study Period | 1,600 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Pre-Intervention: Patients Diagnosed With Conditions of Interest During Study Period | Four population groups were included in the pre-intervention data: 1) adult inpatients with community acquired pneumonia; 2) pediatric inpatients with community acquired pneumonia; 3) adult outpatients with acute pharyngitis; and 4) pediatric outpatients with acute otitis media | 9,935 | 10,167 | OG000 | ClinicalTrials.gov |
| Group 2 | Post-Intervention: Patients Diagnosed With Conditions of Interest During Study Period | Four population groups were included in the post-intervention data: 1) adult inpatients with community acquired pneumonia; 2) pediatric inpatients with community acquired pneumonia; 3) adult outpatients with acute pharyngitis; and 4) pediatric outpatients with acute otitis media | 8,547 | 8,741 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | SECONDARY | ClinicalTrials.gov |
| Title | Guideline-concordant Decision to Prescribe Antibiotics for Pediatric Acute Otitis Media | ClinicalTrials.gov |
| Description | Count of participants with pediatric acute otitis media for which the decision to prescribe an antibiotic was correct. The count of participants with pediatric acute otitis media for which the decision to prescribe an antibiotic was correct was divided by the total number of participants with pediatric acute otitis media to generate the percentage of participants for which the decision to prescribe an antibiotic was correct. These proportions were compared for the group of participants in the pre intervention period (1 year) and the post intervention period (1 year). There were not individual participant level measures for this outcome. | ClinicalTrials.gov |
| Time frame | Pre-intervention and post-intervention, up to 2 years | ClinicalTrials.gov |
| Population | This metric encapsulates patients who did and did not receive antibiotics. | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Using Electronically Derived Automated Reports of Appropriate Antibiotic Use to Inform Stewardship Interventions | ClinicalTrials.gov |
| NCT number | NCT06027593 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Community-acquired Pneumonia, Acute Otitis Media, Pharyngitis | ClinicalTrials.gov |
| Interventions | Quasi experimental intervention | ClinicalTrials.gov |
| Lead sponsor | Children's Hospital of Philadelphia | ClinicalTrials.gov |
| Results first posted | 2025-11-14 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT06027593?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.