Comparison · NCT06053541-deaths
Tiotropium Treatment - MAT1 vs Glycopyrronium Treatment - MAT2: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Tiotropium Treatment - MAT1 vs Glycopyrronium Treatment - MAT2: deaths from any cause. Trial comparisons, record NCT06053541-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT06053541-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0782 | 0.0601 | 0.101 | wilson | |
| Risk in group 2 | 0.0876 | 0.0696 | 0.11 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00939 | -0.038 | 0.0198 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.893 | 0.631 | 1.26 | log | |
| Odds ratio, group 1 over group 2 | 0.884 | 0.605 | 1.29 | log | |
| Number needed to treat, for one fewer death from any cause on Tiotropium Treatment - MAT1 than on Glycopyrronium Treatment - MAT2 | 107 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Tiotropium Treatment - MAT1 | In the MAT1 (total arithmetic mean 1) period, August 2017 to July 2018 data cut available in the DATASUS (Unified Health Brazilian System Informatics Department (in Portuguese)), patients received Tiotropium bromide in soft mist inhaler (SPIRIVA® RESPIMAT®) as part of the treatment plan for Chronic Obstructive Pulmonary Disease (COPD) defined by the Health State Secretariat of Distrito Federal (DF) in Brazil. | 52 | 665 | EG000 |
| Group 2 | Glycopyrronium Treatment - MAT2 | In the MAT2 (total arithmetic mean 2) period, August 2018 to July 2019 data cut available in the DATASUS (Unified Health Brazilian System Informatics Department (in Portuguese), patients received Glycopyrronium bromide in dry powder inhaler (Seebri® Breezhaler®) as part of the treatment plan for Chronic Obstructive Pulmonary Disease (COPD) defined by the Health State Secretariat of Distrito Federal (DF) in Brazil. | 67 | 765 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
Source ClinicalTrials.gov
Trial
- Title
- Morbid Rates After Spiriva Chronic Obstructive Pulmonary Disease (COPD) Protocol Change
- NCT number
- NCT06053541
- Phases
- Conditions
- Pulmonary Disease, Chronic Obstructive
- Interventions
- Lead sponsor
- Boehringer Ingelheim
- Results first posted
- 2024-10-26
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT06053541?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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