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Disease · HP_0000737

Comparisons in its trials26

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
All AVP-786 vs All Placebo: deaths from any cause0 of 1150 of 83198NCT03095066Trial comparisons
All AVP-786 vs All Placebo: serious adverse events3 of 1150 of 83198NCT03095066Trial comparisons
Amantadine vs Placebo: serious adverse events3 of 822 of 86168NCT00779324Trial comparisons
STX209 vs Placebo: serious adverse events1 of 630 of 63126NCT00788073Trial comparisons
Brexpiprazole vs Placebo: deaths from any cause0 of 580 of 57115NCT04174365Trial comparisons
Brexpiprazole vs Placebo: serious adverse events0 of 580 of 57115NCT04174365Trial comparisons
Prior Brexpiprazole vs Prior Placebo: Number of Participants With Suicidality as Measured by Columbia-Suicide Severity Rating Scale (C-SSRS)4 of 492 of 4695NCT04258839Trial comparisons
Prior Brexpiprazole vs Prior Placebo: deaths from any cause0 of 490 of 4695NCT04258839Trial comparisons
Prior Brexpiprazole vs Prior Placebo: Number of Participants With Potentially Clinically Relevant Abnormal Physical Examination Values6 of 494 of 4695NCT04258839Trial comparisons
Prior Brexpiprazole vs Prior Placebo: serious adverse events2 of 491 of 4695NCT04258839Trial comparisons
Carbamazepine vs Placebo: deaths from any cause0 of 350 of 3570NCT00621751Trial comparisons
Carbamazepine vs Placebo: serious adverse events6 of 351 of 3570NCT00621751Trial comparisons
Carbamazepine vs Placebo: Proportion of Participants With Minimal Clinically Important Difference -- Observer Rating20 of 3526 of 3469NCT00621751Trial comparisons
Carbamazepine vs Placebo: Proportion of Participants With Minimal Clinically Important Difference (MCID) -- Participant21 of 3216 of 3062NCT00621751Trial comparisons
Add-on Citalopram Following Optimized Methylphenidate vs Add-on Placebo Following Optimized Methylphenidate: deaths from any cause0 of 230 of 2649NCT00794040Trial comparisons
Add-on Citalopram Following Optimized Methylphenidate vs Add-on Placebo Following Optimized Methylphenidate: serious adverse events0 of 230 of 2649NCT00794040Trial comparisons
Dextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg) vs Placebo: deaths from any cause0 of 200 of 2040NCT03854019Trial comparisons
Dextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg) vs Placebo: serious adverse events0 of 201 of 2040NCT03854019Trial comparisons
Dextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg) vs Placebo: Number of Participants With Behavioral Suicidal Events, as Assessed by the Columbia-Suicide Severity Rating Scale (C-SSRS) - Suicidal Behavior.
0 of 180 of 1836NCT03854019Trial comparisons
Dextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg) vs Placebo: Number of Participants With Behavioral Suicidal Events, as Assessed by the Columbia-Suicide Severity Rating Scale (C-SSRS) - Suicidal Ideation
0 of 180 of 1836NCT03854019Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

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