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Disease · MONDO_0001409

Trials13

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 2 more are not shown, since the checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT01952847Randomized Trial of Glutamine in Patients With Mucositis or EsophagitisPhase 3772022-06-15Advanced CancersGLUTAMINEIts record names the diseaseClinicalTrials.gov
NCT00280150Combination Chemotherapy, Bev, RT, and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung CancerPhase 1/2462017-06-19Lung CancerBEVACIZUMAB, CARBOPLATIN, ERLOTINIB HYDROCHLORIDE, PACLITAXELIts record names the diseaseClinicalTrials.gov
NCT04225026Effects of Intravenous GC4419 on the Incidence and Severity of Esophagitis Due to Chemoradiotherapy for Lung CancerPhase 2392023-03-23EsophagitisAVASOPASEM MANGANESEIts record names the diseaseClinicalTrials.gov
NCT01132638Pantoprazole Magnesium 40 mg Versus Esomeprazole 40 mg in Patients With Erosive Gastroesophageal Reflux DiseasePhase 3713GERDESOMEPRAZOLE, PANTOPRAZOLEIts record names the diseaseClinicalTrials.gov
NCT02860624Ilaprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Chinese PatientsPhase 3550Gastroesophageal Reflux DiseaseESOMEPRAZOLE, ILAPRAZOLEIts record names the diseaseClinicalTrials.gov
NCT06953986A Randomized, Three-Arm Study Comparing Vonaprazan 10 mg, Vonaprazan 20 mg, and Esomeprazole 40 mg for the Healing of LA Grade B or Higher Reflux Esophagitis at 8 WeeksNot applicable414GERDESOMEPRAZOLE, VONOPRAZANIts record names the diseaseClinicalTrials.gov
NCT01400945Efficacy Study of AGSPT201 Tablet to Treat Gastroesophageal Reflux DiseasePhase 3154Gastroesophageal Reflux DiseasePANTOPRAZOLEIts record names the diseaseClinicalTrials.gov
NCT02577393Study of Epigallocatechin-3-gallate (EGCG) for Esophagus Protection in Patients With Lung Cancer Receiving Radial RadiotherapyPhase 283Lung Neoplasms, Esophagitis, Prevention & Control, Epigallocatechin GallateEPIGALOCATECHIN GALLATEIts record names the diseaseClinicalTrials.gov
NCT00006012Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung CancerPhase 1/273Drug/Agent Toxicity by Tissue/Organ, Lung Cancer, Radiation ToxicityAMIFOSTINE, CISPLATIN, ETOPOSIDE, FILGRASTIM, PACLITAXEL, TOPOTECAN HYDROCHLORIDEIts record names the diseaseClinicalTrials.gov
NCT01657578Optimal Dosing of Omeprazole in NeonatesPhase 255Gastroesophageal Reflux Disease (GERD)OMEPRAZOLEIts record names the diseaseClinicalTrials.gov
NCT01336530Tepilta® Versus Oxetacaine, Antacids and PlaceboPhase 340Radiation-induced OesophagitisALUMINUM HYDROXIDE, MAGNESIUM HYDROXIDE, OXETHAZAINEIts record names the diseaseClinicalTrials.gov
NCT00216788The Effect of Nexium on Transmucosal Esophageal LeakPhase 135Reflux, Esophagitis, Barrett's EsophagusESOMEPRAZOLEIts record names the diseaseClinicalTrials.gov
NCT00624546Effect of Antireflux Therapy on the Expression of Genes in Patients With GERD24GERD, Gastroesophageal RefluxESOMEPRAZOLEIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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