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Disease · MONDO_0001505

Comparisons in its trials28

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Prednisone vs Anakinra and Zinc: deaths from any cause12 of 7322 of 74147NCT04072822Trial comparisons
Prednisone vs Anakinra and Zinc: Number of Participants With Infections20 of 7323 of 74147NCT04072822Trial comparisons
Prednisone vs Anakinra and Zinc: serious adverse events41 of 7349 of 74147NCT04072822Trial comparisons
Selonsertib + Prednisolone vs Placebo + Prednisolone: deaths from any cause14 of 509 of 52102NCT02854631Trial comparisons
Selonsertib + Prednisolone vs Placebo + Prednisolone: serious adverse events25 of 5021 of 52102NCT02854631Trial comparisons
Canakinumab vs Placebo: Number of Deaths at Day 902 of 282 of 2755NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Patients With Variceal Haemorrhage Over 90 Days1 of 281 of 2755NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Patients With Encephalopathy Over 90 Days9 of 286 of 2755NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Patients With Infection Over 90 Days6 of 288 of 2755NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Patients With Sepsis Over 90 Days1 of 281 of 2755NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Patients With Acute Kidney Injury Over 90 Days8 of 284 of 2755NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Patients With Ascites Over 90 Days26 of 2821 of 2755NCT03775109Trial comparisons
Canakinumab vs Placebo: deaths from any cause2 of 282 of 2755NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Participants With Treatment-related Adverse Events0 of 280 of 2755NCT03775109Trial comparisons
Canakinumab vs Placebo: serious adverse events10 of 2810 of 2755NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Patients Presenting Histological Improvement of Alcoholic Hepatitis on Liver Biopsy After 28 Days of Treatment Compared to Baseline.14 of 2410 of 2448NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Participants Presenting Changes in Steatosis Grade (NAS) From Baseline to Day 2815 of 2318 of 2346NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Patients Presenting Changes in Presence of Megamitochondria (AHHS) From Baseline to Day 2821 of 2319 of 2346NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Patients Presenting Changes in Degree of Neutrophil Infiltration (AHHS) From Baseline to Day 2821 of 2317 of 2346NCT03775109Trial comparisons
Canakinumab vs Placebo: Number of Patients Presenting Changes in Degree of Fibrosis (AHHS) From Baseline to Day 2823 of 2322 of 2346NCT03775109Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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