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Disease · MONDO_0002928

Trials19

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT03783949European Trial on Enhanced DNA Repair Inhibition in Ovarian CancerPhase 21222025-06-11Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal CarcinomaCARBOPLATIN, GANETESPIB, GEMCITABINE, NIRAPARIB, PACLITAXELIts record names the diseaseClinicalTrials.gov
NCT03395080A Study of DKN-01 as a Monotherapy or in Combination With Paclitaxel in Patients With Recurrent Epithelial Endometrial or Epithelial Ovarian Cancer or CarcinosarcomaPhase 21112023-06-09Endometrial Cancer, Uterine Cancer, Ovarian Cancer, CarcinosarcomaDKN-01, PACLITAXELIts record names the diseaseClinicalTrials.gov
NCT00478426Sunitinib Malate in Treating Patients With Recurrent or Metastatic Endometrial CancerPhase 2342020-02-17
Endometrial Adenocarcinoma, Endometrial Endometrioid Adenocarcinoma, Endometrial Serous Adenocarcinoma, Recurrent Uterine Corpus Carcinoma, Stage IVA Uterine Corpus Cancer AJCC v7, Stage IVB Uterine Corpus Cancer AJCC v7, Uterine Carcinosarcoma, Uterine Corpus Carcinosarcoma
SUNITINIB MALATEIts record names the diseaseClinicalTrials.gov
NCT04513665ZW25 in Women With Endometrial CancersPhase 2162024-10-21Endometrial Cancer, CarcinosarcomaZANIDATAMABIts record names the diseaseClinicalTrials.gov
NCT01061606Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the UterusPhase 282016-11-09Recurrent Uterine Sarcoma, Uterine CarcinosarcomaTEMSIROLIMUSIts record names the diseaseClinicalTrials.gov
NCT06486441Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)Phase 3640Endometrial CancerSACITUZUMAB GOVITECANIts record names the diseaseClinicalTrials.gov
NCT00002546Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Cancer of the UterusPhase 3216SarcomaCISPLATIN, IFOSFAMIDEIts record names the diseaseClinicalTrials.gov
NCT04065269ATr Inhibitor in Combination With Olaparib/Durvalumab (MEDI4736) in Gynaecological Cancers With ARId1A Loss or no LossPhase 2174Gynaecological CancersCERALASERTIB, DURVALUMAB, OLAPARIBIts record names the diseaseClinicalTrials.gov
NCT00003128Ifosfamide With or Without Paclitaxel in Treating Patients With Advanced, Refractory, or Recurrent Cancer of the UterusPhase 3166SarcomaFILGRASTIM, IFOSFAMIDE, PACLITAXELIts record names the diseaseClinicalTrials.gov
NCT03651206Recurrent Ovarian CarcinoSarcoma Anti-pd-1 NiraparibPhase 2/3138Ovarian Carcinosarcoma, Endometrial CarcinosarcomaDOSTARLIMAB, NIRAPARIBIts record names the diseaseClinicalTrials.gov
NCT06940349Interventional Study to Evaluate the Combination of Palbociclib + Sunitinib as a Treatment for Advanced Solid TumorsPhase 1/2100Solid Tumors Refractory to Standard TherapyPALBOCICLIB, SUNITINIBIts record names the diseaseClinicalTrials.gov
NCT02993705Trial On Trabectedin In The Treatment Of Advanced Uterine And Ovarian Carcinosarcoma (CS)Phase 245Carcinosarcoma, Ovarian, Carcinosarcomas UterineTRABECTEDINIts record names the diseaseClinicalTrials.gov
NCT05265793Camrelizumab Combined With Apatinib in the Treatment of Advanced Sarcomatoid Carcinoma or CarcinosarcomaPhase 245PD-1 Immunotherapy, VEGFR-TKI, Sarcomatoid Carcinoma, CarcinosarcomaCAMRELIZUMAB, RIVOCERANIBIts record names the diseaseClinicalTrials.gov
NCT05224999Nivolumab for Recurrent/Metastatic CarcinosarcomaPhase 228Recurrent/Metastatic CarcinosarcomaNIVOLUMABIts record names the diseaseClinicalTrials.gov
NCT05156268A Study of Pembrolizumab and Olaparib in People With Endometrial Cancer or Endometrial CarcinosarcomaPhase 226Endometrial CarcinosarcomaOLAPARIB, PEMBROLIZUMABOpen Targets' reading of its recordClinicalTrials.gov
NCT01454479A Phase I Study of Lapatinib (Tykerb) Plus Ixabepilone (Ixempra) as 2nd-line Treatment for Patients With HER-2 Overexpressed Recurrent or Persistent Endometrial Carcinoma or CarcinosarcomaPhase 124Recurrent Endometrial CancerIXABEPILONE, LAPATINIBIts record names the diseaseClinicalTrials.gov
NCT03935256Adjuvant Sequential & Concurrent CarboTaxol + Radiotherapy for High Risk Endometrial CancerPhase 224Endometrial CancerCARBOPLATIN, PACLITAXELIts record names the diseaseClinicalTrials.gov
NCT03933761
Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression on Substrate Poly ADP Ribose Polymerase Inhibitbor (PARPI) or Chemotherapy
Phase 20Ovarian Cancer, CarcinosarcomaPAMIPARIBIts record names the diseaseClinicalTrials.gov
NCT04149275Cabozantinib Plus Nivolumab and Ipilimumab in Women With Recurrent Gynecologic CarcinosarcomaPhase 20Carcinosarcoma of Ovary, Carcinosarcoma of Uterus, Carcinosarcoma of VaginaCABOZANTINIB, IPILIMUMAB, NIVOLUMABIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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