Disease · MONDO_0003198
Trials15
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.
1 to 15 of 15
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02034110 | Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers | Phase 2 | 206 | 2023-08-21 | Cancer | DABRAFENIB, TRAMETINIB | Its record names the disease | ClinicalTrials.gov |
| NCT00001880 | Stem Cell Transplantation for Metastatic Solid Tumors | Phase 2 | 42 | 2021-11-10 | Neoplasm Metastasis | CYCLOSPORINE, METHOTREXATE | Its record names the disease | ClinicalTrials.gov |
| NCT02949219 | Pembrolizumab in Treating Patients With Small Bowel Adenocarcinoma That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery | Phase 2 | 41 | 2020-01-10 | Metastatic Small Intestinal Adenocarcinoma, Recurrent Small Intestinal Carcinoma, Unresectable Small Intestinal Carcinoma | PEMBROLIZUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT01730586 | Abraxane in CIMP-High Colorectal and Small Bowel Adenocarcinomas | Phase 2 | 34 | 2020-01-18 | Colorectal Cancer, Cancer of Gastrointestinal Tract | PACLITAXEL | Its record names the disease | ClinicalTrials.gov |
| NCT00433550 | Irinotecan, Oxaliplatin, and Capecitabine as First-Line Therapy in Treating Patients With Metastatic or Unresectable Locally Advanced Small Bowel Cancer | Phase 2 | 33 | 2017-08-24 | Small Intestine Adenocarcinoma, Recurrent Small Intestine Cancer | CAPECITABINE, IRINOTECAN HYDROCHLORIDE, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT04491955 | Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal Cancers | Phase 2 | 32 | 2023-11-14 | Small Bowel Cancers, Colorectal Cancers | BINTRAFUSP ALFA, IMMUNOCYTOKINE NHS-IL12, NOGAPENDEKIN ALFA | Its record names the disease | ClinicalTrials.gov |
| NCT00354887 | Capecitabine and Oxaliplatin in Adenocarcinoma of the Small Bowel and Ampulla of Vater | Phase 2 | 31 | 2011-07-14 | Gastrointestinal Cancer | CAPECITABINE, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT01208103 | Bevacizumab, Capecitabine, and Oxaliplatin in Treating Advanced Small Intestinal or Ampulla of Vater Adenocarcinoma | Phase 2 | 30 | 2020-01-18 | Ampulla of Vater Adenocarcinoma, Small Intestinal Adenocarcinoma, Stage III Ampulla of Vater Cancer AJCC v8, Stage III Small Intestinal Adenocarcinoma AJCC v8, Stage IIIA Ampulla of Vater Cancer AJCC v8, Stage IIIA Small Intestinal Adenocarcinoma AJCC v8, Stage IIIB Ampulla of Vater Cancer AJCC v8, Stage IIIB Small Intestinal Adenocarcinoma AJCC v8, Stage IV Ampulla of Vater Cancer AJCC v8, Stage IV Small Intestinal Adenocarcinoma AJCC v8 | BEVACIZUMAB, CAPECITABINE, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT01202409 | CAPOX in KRAS Wild-Type Advanced Adenocarcinoma of the Small Bowel or Ampulla of Vater | Phase 2 | 19 | 2020-02-21 | Gastrointestinal Cancer | PANITUMUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT03000179 | Safety and Efficacy of Avelumab in Small Intestinal Adenocarcinoma | Phase 2 | 8 | 2022-04-14 | Adenocarcinoma | AVELUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT02502370 | Phase III Trial Investigating the Potential Benefit of Adjvant Chemotherapy for Small Bowel Adenocarcinoma | Phase 3 | 100 | Small Bowel Adenocarcinoma, Adjuvant Chemotherapy for SBA | CAPECITABINE, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov | |
| NCT04205968 | Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers | Phase 2 | 94 | Metastatic Small Intestinal Adenocarcinoma, Stage III Small Intestinal Adenocarcinoma AJCC v8, Stage IIIA Small Intestinal Adenocarcinoma AJCC v8, Stage IIIB Small Intestinal Adenocarcinoma AJCC v8, Stage IV Small Intestinal Adenocarcinoma AJCC v8 | FLUOROURACIL, IRINOTECAN, LEUCOVORIN, PACLITAXEL, RAMUCIRUMAB | Its record names the disease | ClinicalTrials.gov | |
| NCT05472948 | Surufatinib and Sintilimab in Combination With Capecitabine for Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma | Phase 2 | 36 | Adenocarcinoma of Small Intestine, Appendix Carcinoma, Metastatic | CAPECITABINE, SINTILIMAB, SURUFATINIB | Its record names the disease | ClinicalTrials.gov | |
| NCT04257461 | A Trial to Evaluate the Potential Benefit of Adjuvant Chemotherapy for Small Bowel Adenocarcinoma | Phase 3 | 30 | Small Bowel Adenocarcinoma | OXALIPLATIN | Its record names the disease | ClinicalTrials.gov | |
| NCT07347314 | Enfortumab Vedotin in Patients With Advanced Small Bowel Adenocarcinoma Refractory or Intolerant to Platinum-based Combination Therapy | Phase 2 | 27 | Advanced Small Bowel Adenocarcinoma | ENFORTUMAB VEDOTIN | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0003198/trials