Disease · MONDO_0004456
Trials29
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.
1 to 20 of 29
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00929253 | Efficacy of Computer Delivered Community Reinforcement Approach (CRA) (Bup II) | Not applicable | 170 | 2022-05-27 | Opiate Addiction | BUPRENORPHINE | Its record names the disease | ClinicalTrials.gov |
| NCT00223236 | Trial of Citicoline Therapy in Patients With Mania or Hypomania and Cocaine Abuse/Dependence | Phase 3 | 44 | 2014-08-11 | Mania, Hypomania, Cocaine Abuse, Cocaine Dependence | CITICOLINE | Its record names the disease | ClinicalTrials.gov |
| NCT00373880 | Effects of Aripiprazole on Cocaine Craving and Self-Administration | Phase 2 | 26 | 2017-09-11 | Cocaine Abuse | ARIPIPRAZOLE | Its record names the disease | ClinicalTrials.gov |
| NCT00218543 | Atomoxetine for Treating Cocaine Abuse in Adults With Attention Deficit Hyperactivity Disorder (ADHD) | Phase 2 | 20 | 2012-07-04 | Attention Deficit Disorder With Hyperactivity, Cocaine-Related Disorders | ATOMOXETINE | Its record names the disease | ClinicalTrials.gov |
| NCT02141620 | n-Acetylcysteine and Cocaine | Early phase 1 | 15 | 2016-10-06 | Cocaine Abuse, Cocaine Dependence | ACETYLCYSTEINE | Its record names the disease | ClinicalTrials.gov |
| NCT02563769 | Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study | Phase 1 | 10 | 2023-11-03 | Cocaine Dependence, Cocaine Addiction, Cocaine Abuse, Cocaine-Related Disorders | CLAVULANIC ACID, COCAINE | Its record names the disease | ClinicalTrials.gov |
| NCT00913484 | Disulfiram for Cocaine Abuse in Buprenorphine Treatment | Phase 2 | 177 | Cocaine Dependence, Opioid Dependency | DISULFIRAM | Its record names the disease | ClinicalTrials.gov | |
| NCT00218166 | Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of Cocaine | Phase 2 | 78 | Cocaine-Related Disorders | BACLOFEN, TIAGABINE | Its record names the disease | ClinicalTrials.gov | |
| NCT01030692 | Rivastigmine and Huperzine A as Treatments for Cocaine Dependence | Phase 1 | 72 | Cocaine Dependence, Cocaine Addiction, Cocaine Abuse, Substance Abuse | HUPERZINE A, RIVASTIGMINE | Its record names the disease | ClinicalTrials.gov | |
| NCT01601730 | Modafinil - Escitalopram Study for Cocaine Dependence | Phase 1 | 68 | Cocaine Dependence, Cocaine Abuse, Cocaine Addiction, Substance Abuse | ESCITALOPRAM, MODAFINIL | Its record names the disease | ClinicalTrials.gov | |
| NCT01366001 | ALK33BUP-101: Safety and Pharmacodynamic Effects of ALKS 33-BUP Administered Alone and When Co-administered With Cocaine | Phase 1 | 33 | Cocaine Abuse | BUPRENORPHINE, SAMIDORPHAN | Its record names the disease | ClinicalTrials.gov | |
| NCT01062945 | The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine | Phase 1 | 13 | Cocaine Addiction, Cocaine Abuse, Cocaine Dependence, Substance Abuse | COCAINE, DOXAZOSIN | Its record names the disease | ClinicalTrials.gov | |
| NCT01651364 | A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence | Phase 1 | 11 | Cocaine Dependence, Cocaine Abuse, Cocaine Addiction, Substance Abuse | CABERGOLINE | Its record names the disease | ClinicalTrials.gov | |
| NCT01651377 | Pramipexole as a Treatment for Cocaine Dependence | Phase 1 | 10 | Cocaine Addiction, Cocaine Abuse, Cocaine Dependence, Substance Abuse | PRAMIPEXOLE | Its record names the disease | ClinicalTrials.gov | |
| NCT00000203 | Buprenorphine Maintenance for Opioid Addicts - 2 | Phase 2 | 0 | Opioid-Related Disorders | BUPRENORPHINE | Its record names the disease | ClinicalTrials.gov | |
| NCT00000212 | IV Cocaine Abuse: A Laboratory Model - 1 | Phase 2 | 0 | Cocaine-Related Disorders | DESIPRAMINE | Its record names the disease | ClinicalTrials.gov | |
| NCT00000213 | IV Cocaine Abuse: A Laboratory Model - 2 | Phase 2 | 0 | Cocaine-Related Disorders | FLUOXETINE | Its record names the disease | ClinicalTrials.gov | |
| NCT00000214 | IV Cocaine Abuse: A Laboratory Model - 3 | Phase 2 | 0 | Cocaine-Related Disorders | BUPRENORPHINE | Its record names the disease | ClinicalTrials.gov | |
| NCT00000215 | IV Cocaine Abuse: A Laboratory Model - 4 | Phase 2 | 0 | Cocaine-Related Disorders | PERGOLIDE | Its record names the disease | ClinicalTrials.gov | |
| NCT00000216 | Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1 | Phase 3 | 0 | Cocaine-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders | BUPRENORPHINE, METHADONE | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0004456/trials