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Disease · MONDO_0004989

Comparisons in its trials12

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Tuc+Cap+Tra vs Pbo+Cap+Tra: deaths from any cause262 of 410152 of 202612NCT02614794Trial comparisons
Tuc+Cap+Tra vs Pbo+Cap+Tra: serious adverse events124 of 40462 of 197601NCT02614794Trial comparisons
Tucatinib+ Ado-trastuzumab Emtansine vs Placebo+ Ado-trastuzumab Emtansine: Number of Participants With Treatment Emergent Adverse Events (AEs)230 of 231233 of 233464NCT03975647Trial comparisons
Placebo+ Ado-trastuzumab Emtansine vs Tucatinib+ Ado-trastuzumab Emtansine: deaths from any cause63 of 23371 of 231464NCT03975647Trial comparisons
Placebo+ Ado-trastuzumab Emtansine vs Tucatinib+ Ado-trastuzumab Emtansine: serious adverse events52 of 23370 of 231464NCT03975647Trial comparisons
Cisplatin and Cetuximab vs Cisplatin: Safety- Number of Participants Experiencing Any Adverse Event (AE)114 of 11457 of 57171NCT00463788Trial comparisons
Colorectal Cancer vs Non-Colorectal Cancer Cohort vs Breast and Ovarian Cohorts: deaths from any cause1 of 250 of 2651NCT00088413Trial comparisons
Colorectal Cancer and Non-Colorectal Cancer Cohort vs Breast Cancer and Ovarian Cancer Cohort: Number of Participants With Adverse Events Assessed by the Common Terminology Criteria in Adverse Events (CTCAE) v3.0 and v4.0
25 of 2526 of 2651NCT00088413Trial comparisons
Colorectal Cancer vs Non-Colorectal Cancer Cohort vs Breast and Ovarian Cohorts: serious adverse events25 of 2526 of 2651NCT00088413Trial comparisons
Dose Level 1 - Docetaxel 75 mg/m^2 vs Dose Level 2 - Docetaxel 60 mg/m^2: serious adverse events2 of 27 of 2931NCT00086957Trial comparisons
Colorectal Cancer Cohort vs Non-Colorectal Cancer Cohort: Number of Participants With an Positive Immune Response to Carcinoembryonic Antigen (CEA) Peptide and/or Protein in the Colorectal Cancer and Non-colorectal Cancer Cohort Post Vaccination
3 of 96 of 918NCT00088413Trial comparisons
Breast Cancer Cohort vs Ovarian Cancer Cohort: Number of Participants With an Positive Immune Response to Carcinoembryonic Antigen (CEA) Peptide and/or Protein in the Breast Cancer and Ovarian Cancer Cohorts Post Vaccination
1 of 31 of 25NCT00088413Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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