Disease · MONDO_0005113
Trials41
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.
1 to 20 of 41
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00627393 | Safety and Effectiveness of Granulocyte Transfusions in Resolving Infection in People With Neutropenia (The RING Study) | Phase 3 | 114 | 2014-12-23 | Neutropenia, Infection | DEXAMETHASONE | Its record names the disease | ClinicalTrials.gov |
| NCT00608959 | Study of Antimicrobial Activity of Omiganan 1% Gel vs. Chlorhexidine 2% for Topical Skin Antisepsis in Healthy Adult Subjects | Phase 3 | 30 | 2010-01-25 | Infection | CHLORHEXIDINE, OMIGANAN | Its record names the disease | ClinicalTrials.gov |
| NCT05217537 | Study to Evaluate the PK of IV and PO Omadacycline in Children and Adolescents With Suspected or Confirmed Bacterial Infections | Phase 1 | 23 | 2026-03-09 | Bacterial Infections | OMADACYCLINE | Open Targets' reading of its record | ClinicalTrials.gov |
| NCT02013141 | Telavancin Pediatric PK Study (Ages >12 Months to 17 Years) | Phase 1 | 22 | 2024-06-24 | Gram-Positive Bacterial Infections | TELAVANCIN | Its record names the disease | ClinicalTrials.gov |
| NCT03587428 | Effect of Two Toothpastes on Bacteria in Saliva | Not applicable | 15 | 2019-07-15 | Oral Health | SODIUM CITRATE, ZINC CHLORIDE | Its record names the disease | ClinicalTrials.gov |
| NCT03651895 | Metformin to Reduce Airway Glucose in COPD Patients | Phase 2 | 14 | 2025-02-18 | Chronic Obstructive Pulmonary Disease | METFORMIN | Its record names the disease | ClinicalTrials.gov |
| NCT01401010 | Pharmacokinetic/Pharmacodynamic Study of Doripenem in Febrile Neutropenic Patients | Phase 4 | 12 | 2012-06-05 | Febrile Neutropenia | DORIPENEM | Its record names the disease | ClinicalTrials.gov |
| NCT01157533 | Utility of Vancomycin Loading: A Pharmacokinetic Analysis in Critically Ill Patients | Not applicable | 1 | 2013-03-18 | Infection | VANCOMYCIN | Its record names the disease | ClinicalTrials.gov |
| NCT02208154 | Ecological Effects of Decolonisation Strategies in Intensive Care | Phase 3 | 8,665 | ICU-ecology (Multidrug Resistant Bacteria), ICU-acquired Bacteraemia | CHLORHEXIDINE, COLISTIN, NYSTATIN, TOBRAMYCIN | Open Targets' reading, confirmed by NLM's indexing of its papers | ClinicalTrials.gov | |
| NCT02573610 | Study of DE-108 Ophthalmic Solution in Patients Who Are Scheduled for Cataract Surgery | Phase 3 | 576 | Cataract Surgery | LEVOFLOXACIN | Its record names the disease | ClinicalTrials.gov | |
| NCT00173901 | Adverse Drug Reactions of Different Brands of Ceftazidime Injection | Phase 4 | 536 | Infection | CEFTAZIDIME | Open Targets' reading of its record | ClinicalTrials.gov | |
| NCT03247920 | Reduction of Intravenous Antibiotics In Neonates | Phase 4 | 510 | Neonatal Infection, Neonatal SEPSIS | AMOXICILLIN, CLAVULANIC ACID | Its record names the disease | ClinicalTrials.gov | |
| NCT01344070 | Generic Formulations of Commonly-used Oral Drugs in Saudi Arabia:Interchangeability & Post-marketing Quality | Not applicable | 500 | Generic Drug Quality, Generic Formulation Interchangeability | ACETAMINOPHEN, AMLODIPINE, AMOXICILLIN, ATENOLOL, CEPHALEXIN, CIPROFLOXACIN, CLARITHROMYCIN, DICLOFENAC, ENALAPRIL, FLUCONAZOLE, IBUPROFEN, METFORMIN, METRONIDAZOLE, OMEPRAZOLE, RANITIDINE | Open Targets' reading of its record | ClinicalTrials.gov | |
| NCT00189384 | Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants | Phase 3 | 426 | Bacterial Infection, Sepsis, Infant, Newborn | CEFTRIAXONE, GENTAMICIN, PENICILLIN G PROCAINE | Its record names the disease | ClinicalTrials.gov | |
| NCT03425448 | Neutrolin Versus Heparin for Locking Hemodialysis Catheters | Not applicable | 192 | Hemodialysis Catheter Infection, Catheter Thrombosis | HEPARIN | Open Targets' reading of its record | ClinicalTrials.gov | |
| NCT05535075 | Model-informed Precision Dosing of Vancomycin in Adults | Phase 4 | 155 | Vancomycin | VANCOMYCIN | Its record names the disease | ClinicalTrials.gov | |
| NCT03726216 | Xydalba Utilization Registry in France | 151 | Bacterial Infections | DALBAVANCIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT05388747 | Population Pharmacokinetics, Effectiveness and Safety of Cefuroxime in Neonates | 100 | Infectious Disease | CEFUROXIME | Open Targets' reading of its record | ClinicalTrials.gov | ||
| NCT00057369 | Safety and Efficacy of Dalbavancin Versus Vancomycin in the Treatment of Catheter-Related Bloodstream Infections | Phase 2 | 88 | Bacteremia | DALBAVANCIN | Its record names the disease | ClinicalTrials.gov | |
| NCT02268279 | Pharmacokinetics and Safety of Solithromycin in Adolescents and Children | Phase 1 | 84 | Bacterial Infection | SOLITHROMYCIN | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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GET https://conductscience.org/api/diseases/v1/MONDO_0005113/trials