Disease · MONDO_0005149
Comparisons in its trials64
Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.
1 to 20 of 64
Download this page as JSON| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Ambrisentan vs Placebo: serious adverse events | 73 of 329 | 25 of 163 | 492 | NCT00768300 | Trial comparisons |
| Inhaled Treprostinil vs Placebo: Incidence of Clinical Worsening | 37 of 163 | 54 of 163 | 326 | NCT02630316 | Trial comparisons |
| Active Inhaled Treprostinil vs Placebo: deaths from any cause | 10 of 163 | 12 of 163 | 326 | NCT02630316 | Trial comparisons |
| Active Inhaled Treprostinil vs Placebo: serious adverse events | 38 of 163 | 42 of 163 | 326 | NCT02630316 | Trial comparisons |
| Sildenafil vs Placebo: Change in 6-minute Walk Distance From Enrollment to Week 12 (≥ 20% Improvement) | 9 of 89 | 6 of 91 | 180 | NCT00517933 | Trial comparisons |
| Sildenafil vs Placebo: serious adverse events | 13 of 89 | 15 of 91 | 180 | NCT00517933 | Trial comparisons |
| Pirfenidone+Sildenafil vs Pirfenidone+Placebo: deaths from any cause | 28 of 88 | 36 of 89 | 177 | NCT02951429 | Trial comparisons |
| Pirfenidone+Sildenafil vs Pirfenidone+Placebo: serious adverse events | 54 of 88 | 55 of 89 | 177 | NCT02951429 | Trial comparisons |
| Riociguat up to 2.5 mg Tid vs Placebo: Number of Serious Adverse Events During Safety Follow-up Phase | 18 of 73 | 14 of 74 | 147 | NCT02138825 | Trial comparisons |
| Inhaled Nitric Oxide (iNO) vs Placebo (Nitrogen): Necrotizing Enterocolitis (NEC) | 5 of 59 | 10 of 65 | 124 | NCT00955487 | Trial comparisons |
| Inhaled Nitric Oxide (iNO) vs Placebo (Nitrogen): Threshold Retinopathy of Prematurity (ROP) | 3 of 59 | 4 of 65 | 124 | NCT00955487 | Trial comparisons |
| Inhaled Nitric Oxide (iNO) vs Placebo (Nitrogen): Symptomatic PDA Requiring Surgical Ligation | 3 of 59 | 8 of 65 | 124 | NCT00955487 | Trial comparisons |
| Inhaled Nitric Oxide (iNO) vs Placebo (Nitrogen): Severe Intracranial Hemorrhage | 2 of 59 | 4 of 65 | 124 | NCT00955487 | Trial comparisons |
| Inhaled Nitric Oxide (iNO) vs Placebo (Nitrogen): Sepsis | 13 of 59 | 14 of 65 | 124 | NCT00955487 | Trial comparisons |
| Inhaled Nitric Oxide (iNO) vs Placebo (Nitrogen): deaths from any cause | 2 of 59 | 4 of 65 | 124 | NCT00955487 | Trial comparisons |
| Inhaled Nitric Oxide (iNO) vs Placebo (Nitrogen): Symptomatic PDA Requiring Medical Treatment | 1 of 59 | 2 of 65 | 124 | NCT00955487 | Trial comparisons |
| Inhaled Nitric Oxide (iNO) vs Placebo (Nitrogen): serious adverse events | 27 of 59 | 42 of 65 | 124 | NCT00955487 | Trial comparisons |
| Oral Treprostinil vs Placebo: deaths from any cause | 0 of 41 | 1 of 43 | 84 | NCT03037580 | Trial comparisons |
| Oral Treprostinil vs Placebo: serious adverse events | 11 of 41 | 8 of 43 | 84 | NCT03037580 | Trial comparisons |
| Sildenafil vs Placebo: serious adverse events | 17 of 37 | 8 of 37 | 74 | NCT00492531 | Trial comparisons |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0005149/comparisons