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Disease · MONDO_0005313

Trials13

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 2 more are not shown, since the checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT01827358Safety and Efficacy of Mupirocin in Eradicating Colonization With S. Aureus in Critically Ill InfantsPhase 21552017-07-07Staphylococcal InfectionMUPIROCINIts record names the diseaseClinicalTrials.gov
NCT01222585Metronidazole Pharmacokinetics (PK) in Premature InfantsPhase 1242013-12-18Serious Systemic Infections, Necrotizing EnterocolitisMETRONIDAZOLEIts record names the diseaseClinicalTrials.gov
NCT01156480Anti-inflammatory Treatment at the Onset of Necrotizing Enterocolitis (NEC) in Preterm InfantsNot applicable22014-03-24Necrotizing EnterocolitisHYDROCORTISONEIts record names the diseaseClinicalTrials.gov
NCT04347720Canadian National PDA Treatment Study1,663Patent Ductus Arteriosus, Extreme PrematurityACETAMINOPHEN, IBUPROFEN, INDOMETHACINIts record names the diseaseClinicalTrials.gov
NCT02884219Early Treatment Versus Expectative Management of PDA in Preterm InfantsNot applicable273Patent Ductus ArteriosusIBUPROFEN, INDOMETHACINIts record names the diseaseClinicalTrials.gov
NCT03860428Early Treatment Versus Expectant Management of PDA in Preterm InfantsNot applicable208Patent Ductus ArteriosusACETAMINOPHEN, IBUPROFENIts record names the diseaseClinicalTrials.gov
NCT06048614Saline Enema Administration in Meconium Obstruction of Prematurity and Impact on the Resolution, Feeds, Microbiome, and Gut-brain Axis.Not applicable95Meconium Obstruction of PrematurityGLYCERIN, SODIUM CHLORIDEIts record names the diseaseClinicalTrials.gov
NCT02819414Paracetamol Treatment of the Borderline Significant PDAPhase 280Patent Ductus ArteriosusACETAMINOPHENIts record names the diseaseClinicalTrials.gov
NCT06422000Effect of Pentoxifylline Versus Probiotic on Preterm Neonates With Necrotizing EnterocolitisPhase 375Necrotizing EnterocolitisPENTOXIFYLLINEIts record names the diseaseClinicalTrials.gov
NCT04696003Treatment of Classic Mid-trimester PPROM by Means of Continuous AmnioinfusionPhase 368Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intracranial HemorrhagesAMOXICILLIN, AZITHROMYCIN, CLARITHROMYCINIts record names the diseaseClinicalTrials.gov
NCT00271336Pentoxifylline in the Treatment of NEC in Premature NeonatesPhase 250Necrotizing EnterocolitisPENTOXIFYLLINEIts record names the diseaseClinicalTrials.gov
NCT02050971Autologous Cord Blood Infusion for the Prevention and Treatment of Prematurity Complications In Preterm NeonatesPhase 140Anemia, Neonatal, Intracranial Hemorrhages, Necrotizing Enterocolitis, Respiratory Distress Syndrome, Newborn, Retinopathy of Prematurity, Bronchopulmonary DysplasiaAUTOLOGOUS CORD BLOODIts record names the diseaseClinicalTrials.gov
NCT06547424Phase I Clinical Study of Chondroitin Sulfate for Treatment of NECPhase 10Necrotizing Enterocolitis, Intestinal IschemiaCHONDROITIN SULFATEIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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