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Disease · MONDO_0005419

Comparisons in its trials33

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Modafinil vs Placebo: Reduction of Craving32 of 14210 of 68210NCT00520286Trial comparisons
Modafinil vs Placebo: serious adverse events0 of 1425 of 68210NCT00520286Trial comparisons
Bupropion vs Placebo: Treatment Success Among Subjects With 18 or Less Days of Methamphetamine Use65 of 10076 of 104204NCT00687713Trial comparisons
Bupropion vs Placebo: Number of Subjects Showing Abstinence14 of 10020 of 104204NCT00687713Trial comparisons
Bupropion vs Placebo: serious adverse events1 of 1003 of 104204NCT00687713Trial comparisons
Topiramate vs Placebo Oral Tablet: serious adverse events3 of 698 of 71140NCT00345371Trial comparisons
Ibudilast vs Placebo: Methamphetamine Use9 of 6410 of 61125NCT01860807Trial comparisons
Ibudilast vs Placebo: deaths from any cause0 of 640 of 61125NCT01860807Trial comparisons
Ibudilast vs Placebo: serious adverse events2 of 641 of 61125NCT01860807Trial comparisons
Citicoline vs Placebo: serious adverse events2 of 720 of 32104NCT00950352Trial comparisons
Aripiprazole vs Placebo: serious adverse events3 of 454 of 4590NCT00497055Trial comparisons
Modafinil vs Placebo: Retention14 of 3413 of 3771NCT00469508Trial comparisons
Modafinil vs Placebo: serious adverse events3 of 341 of 3771NCT00469508Trial comparisons
Active Comparator: vs Placebo Comparator:: serious adverse events1 of 301 of 3060NCT00497081Trial comparisons
Naltrexone With Ecological Momentary Intervention vs Placebo With Ecological Momentary Intervention: deaths from any cause0 of 400 of 2060NCT04791969Trial comparisons
Naltrexone With Ecological Momentary Intervention vs Placebo With Ecological Momentary Intervention: serious adverse events2 of 400 of 2060NCT04791969Trial comparisons
Vigabatrin vs Placebo: The Proportion of Subjects in Each Treatment Group Who Are Amphetamine Abstinent During the Last 2 Weeks of the Treatment Phase (Weeks 11 and 12).4 of 282 of 2755NCT00730522Trial comparisons
Vigabatrin vs Placebo: deaths from any cause0 of 280 of 2755NCT00730522Trial comparisons
Vigabatrin vs Placebo: serious adverse events2 of 280 of 2755NCT00730522Trial comparisons
Sugar Pill vs Varenicline: End of Treatment Abstinence5 of 254 of 2752NCT01365819Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005419/comparisons