ConductScience.org, home

Disease · MONDO_0005627

Comparisons in its trials54

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Pemetrexed/Cisplatin vs Placebo/Cisplatin: serious adverse events185 of 392132 of 385777NCT00415194Trial comparisons
IMRT vs IMRT Plus Cetuximab: deaths from any cause97 of 28787 of 290577NCT00956007Trial comparisons
IMRT vs IMRT Plus Cetuximab: serious adverse events50 of 28283 of 276558NCT00956007Trial comparisons
Induction Plus Chemoradiotherapy vs Chemoradiotherapy: deaths from any cause39 of 13842 of 135273NCT00117572Trial comparisons
Induction Plus Chemoradiotherapy vs Chemoradiotherapy: serious adverse events65 of 13838 of 135273NCT00117572Trial comparisons
IMRT + Cisplatin + Placebo vs IMRT + Cisplatin + Lapatinib: deaths from any cause23 of 6426 of 63127NCT01711658Trial comparisons
IMRT + Cisplatin + Placebo vs IMRT + Cisplatin + Lapatinib: serious adverse events26 of 5931 of 60119NCT01711658Trial comparisons
Panitumumab Plus Chemotherapy vs Chemotherapy Alone: serious adverse events34 of 5627 of 55111NCT00454779Trial comparisons
A: Cetuximab+FHX vs B: Cetuximab + PX: Objective Response Rate to CRT3 of 574 of 53110NCT00468169Trial comparisons
A: Cetuximab+FHX vs B: Cetuximab + PX: deaths from any cause14 of 579 of 53110NCT00468169Trial comparisons
A: Cetuximab+FHX vs B: Cetuximab + PX: Residual Lymph Node Disease2 of 576 of 53110NCT00468169Trial comparisons
A: Cetuximab+FHX vs B: Cetuximab + PX: serious adverse events7 of 5714 of 53110NCT00468169Trial comparisons
Boost Arm vs Control Arm: deaths from any cause15 of 4114 of 59100NCT02031250Trial comparisons
Boost Arm vs Control Arm: serious adverse events12 of 4115 of 59100NCT02031250Trial comparisons
Boost Arm vs Control Arm: Local-regional Control Rate7 of 4015 of 4181NCT02031250Trial comparisons
Boost Arm vs Control Arm: Proportion of Patients in Which Hypoperfused/Low-diffusion Subvolumes Overlap With Recurrence Volumes12 of 4012 of 4181NCT02031250Trial comparisons
Arm A (Cetuximab and Temsirolimus) vs Arm B (Temsirolimus): serious adverse events14 of 4019 of 4080NCT01256385Trial comparisons
Cisplatin + Radiation + Pembrolizumab - Concurrent vs Cisplatin + Radiation + Pembrolizumab - Sequential: Acute Toxicity / DLT Rate3 of 410 of 3980NCT02777385Trial comparisons
Cisplatin + Radiation + Pembrolizumab - Concurrent vs Cisplatin + Radiation + Pembrolizumab - Sequential: deaths from any cause11 of 416 of 3980NCT02777385Trial comparisons
Cisplatin + Radiation + Pembrolizumab - Concurrent vs Cisplatin + Radiation + Pembrolizumab - Sequential: serious adverse events21 of 4110 of 3980NCT02777385Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005627/comparisons