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Disease · MONDO_0005921

Comparisons in its trials18

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Pyronaridine Artesunate vs Chloroquine: deaths from any cause2 of 2280 of 228456NCT00440999Trial comparisons
Pyronaridine Artesunate vs Chloroquine: serious adverse events2 of 2280 of 228456NCT00440999Trial comparisons
TQ+CQ vs PQ+CQ: Number of Participants With P. Falciparum4 of 1663 of 85251NCT02216123Trial comparisons
TQ+CQ vs PQ+CQ: Number of Participants With Recrudescence0 of 1660 of 85251NCT02216123Trial comparisons
TQ+CQ vs PQ+CQ: deaths from any cause0 of 1660 of 85251NCT02216123Trial comparisons
TQ+CQ vs PQ+CQ: serious adverse events6 of 1661 of 85251NCT02216123Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: deaths from any cause0 of 840 of 75159NCT04222088Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: serious adverse events0 of 840 of 75159NCT04222088Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: Adequate Clinical and Parasitological Response (ACPR)74 of 7572 of 74149NCT04222088Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: Early Treatment Failure (ETF)0 of 750 of 74149NCT04222088Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: Late Clinical Failure (LCF)1 of 750 of 74149NCT04222088Trial comparisons
Artemether-lumefantrine (Coartem™) + Primaquine vs Chloroquine + Primaquine: Late Parasitological Failure (LPF)0 of 752 of 74149NCT04222088Trial comparisons
Cohort 1 Tafenoquine vs Cohort 1-Chloroquine: deaths from any cause0 of 460 of 2470NCT01290601Trial comparisons
Cohort 1 Tafenoquine vs Cohort 1-Chloroquine: serious adverse events5 of 460 of 2470NCT01290601Trial comparisons
Pyronaridine - Artesunate vs Chloroquine: deaths from any cause0 of 150 of 1530NCT04368910Trial comparisons
Pyronaridine - Artesunate vs Chloroquine: serious adverse events0 of 150 of 1530NCT04368910Trial comparisons
DSM265 P. Falciparum vs OZ439 P. Vivax: deaths from any cause0 of 80 of 816NCT02573857Trial comparisons
DSM265 P. Falciparum vs OZ439 P. Vivax: serious adverse events0 of 80 of 816NCT02573857Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005921/comparisons