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Disease · MONDO_0005984

Comparisons in its trials21

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
NAFT-600 vs Placebo: serious adverse events1 of 5722 of 287859NCT01290341Trial comparisons
NAFT-600 vs Placebo: serious adverse events2 of 5712 of 284855NCT01289015Trial comparisons
Test: Ketoconazole Cream 2% vs Reference: Ketoconazole Cream 2%: Secondary Efficacy Endpoint: The Number of Patients in Each Treatment Group With a Clinical Cure of Tinea Pedis (Equivalence: Per-Protocol Population)
97 of 184110 of 191375NCT03824912Trial comparisons
Test: Ketoconazole Cream 2% vs Reference: Ketoconazole Cream 2%: Primary Efficacy Endpoint: The Number of Patients in Each Treatment Group With a Therapeutic Cure of Tinea Pedis (Equivalence: Per-Protocol Population)
89 of 18490 of 191375NCT03824912Trial comparisons
Test: Ketoconazole Cream 2% vs Reference: Ketoconazole Cream 2%: Secondary Efficacy Endpoint:The Number of Patients in Each Treatment Group With a Mycological Cure of Tinea Pedis (Equivalence: Per-Protocol Population)
127 of 184118 of 190374NCT03824912Trial comparisons
Test vs Reference Standard: Proportion of Patients in Each Active Treatment Group Who Are Considered a Therapeutic Cure96 of 18581 of 170355NCT03129321Trial comparisons
Test vs Reference Standard: Proportion of Patients in Each Active Treatment Group Who Are Considered a Mycological Cure136 of 185125 of 170355NCT03129321Trial comparisons
Test vs Reference Standard: Proportion of Patients in Each Active Treatment Group Who Are Considered a Clinical Cure (Patient's Total Severity Score Must be ≤ 2 With no Individual Severity Score > 1)113 of 18599 of 170355NCT03129321Trial comparisons
NAFT-500 vs Placebo-2wks: serious adverse events0 of 1660 of 168334NCT00750152Trial comparisons
Terbinafine vs Placebo: Number of Subjects With Adverse Event9 of 14611 of 144290NCT01433107Trial comparisons
Terbinafine vs Placebo: serious adverse events0 of 1460 of 144290NCT01433107Trial comparisons
Econazole Nitrate Foam 1% vs Vehicle Foam: serious adverse events0 of 1301 of 134264NCT01353976Trial comparisons
Terbinafine vs Placebo: Effective Treatment Outcome (Direct Microscopy and Culture Negative and Total Signs and Symptom Score Less or Equal to 2)73 of 11510 of 122237NCT01433107Trial comparisons
Luliconazole Cream 1% vs Vehicle Cream: serious adverse events0 of 600 of 1575NCT02767947Trial comparisons
Tinea Pedis vs Tinea Cruris: serious adverse events0 of 150 of 1530NCT02767271Trial comparisons
Nitric Oxide vs Control: deaths from any cause0 of 130 of 720NCT02871011Trial comparisons
Nitric Oxide vs Control: serious adverse events0 of 130 of 720NCT02871011Trial comparisons
Nitric Oxide vs Control: Number of Participants With Complete Cure: Post Treatment (Day 31)5 of 80 of 412NCT02871011Trial comparisons
Nitric Oxide vs Control: Number of Participants With Therapeutic Failure: Post Treatment (Day 17)0 of 82 of 412NCT02871011Trial comparisons
Nitric Oxide vs Control: Number of Participants withTherapeutic Failure: Post Treatment Day 31 AND a Post Treatment Clinical Symptom Severity Score (Day 31) of < 8.0 of 81 of 412NCT02871011Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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