Disease · MONDO_0006939
Trials16
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.
1 to 16 of 16
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03357614 | Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults | Phase 3 | 1,395 | 2020-12-29 | Complicated Urinary Tract Infections | PROBENECID, SULOPENEM, SULOPENEM ETZADROXIL | Its record names the disease | ClinicalTrials.gov |
| NCT01345929 | Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Urinary Tract Infection, Including Pyelonephritis | Phase 3 | 558 | 2015-01-15 | Complicated Urinary Tract Infection, Pyelonephritis | CEFTOLOZANE, LEVOFLOXACIN, TAZOBACTAM | Its record names the disease | ClinicalTrials.gov |
| NCT03230838 | MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034) | Phase 2 | 134 | 2021-12-01 | Complicated Urinary Tract Infection, Pyelonephritis | CEFTOLOZANE, TAZOBACTAM | Its record names the disease | ClinicalTrials.gov |
| NCT00921024 | Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections | Phase 2 | 129 | 2015-01-15 | Complicated Urinary Tract Infection | CEFTAZIDIME, CEFTOLOZANE | Its record names the disease | ClinicalTrials.gov |
| NCT02728089 | Study of Ceftolozane/Tazobactam (MK-7625A) in Japanese Participants With Uncomplicated Pyelonephritis and Complicated Urinary Tract Infection (MK-7625A-014) | Phase 3 | 115 | 2018-09-19 | Urinary Tract Infection (UTI), Complicated Urinary Tract Infection, Pyelonephritis, Uncomplicated Pyelonephritis | CEFTOLOZANE | Its record names the disease | ClinicalTrials.gov |
| NCT02302092 | An Efficacy and Safety of Flomoxef Versus Cefepime in the Treatment of Participants With Urinary Tract Infections | Phase 3 | 13 | 2017-10-27 | Urinary Tract Infection | CEFEPIME, FLOMOXEF | Its record names the disease | ClinicalTrials.gov |
| NCT00229021 | Doripenem in the Treatment of Complicated Lower Urinary Tract Infection or Pyelonephritis | Phase 3 | 741 | Urinary Tract Infections, Pyelonephritis | DORIPENEM | Its record names the disease | ClinicalTrials.gov | |
| NCT00210990 | Doripenem in the Treatment of Complicated Lower Urinary Tract Infection or Pyelonephritis | Phase 3 | 403 | Urinary Tract Infections, Pyelonephritis | DORIPENEM | Its record names the disease | ClinicalTrials.gov | |
| NCT01406275 | Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media) | 363 | Otitis Maedia | AMOXICILLIN, CLAVULANIC ACID | Its record names the disease | ClinicalTrials.gov | ||
| NCT06144060 | A Trial of Intravenous HRS-8427 in the Treatment of Adults With Complicate Urinary Tract Infection, Including Acute Pyelonephritis | Phase 2 | 126 | Patients With Complicated Urinary Tract Infection(cUTI), Including Acute Pyelonephritis(AP) | IMIPENEM | Its record names the disease | ClinicalTrials.gov | |
| NCT03557840 | Plasma Protein Binding and PK/PD of Total and Unbound Temocillin Non-ICU Patients | Not applicable | 60 | Pharmacokinetics, Antibacterial Agents, Infections, Bacterial, Infection, Drug Monitoring, Temocillin | TEMOCILLIN | Its record names the disease | ClinicalTrials.gov | |
| NCT04735042 | SGLT-2 and DPP-4 Inhibition, Subclinical Inflammation of the Genito-urinary Tract and Risk of Infections. | 60 | Type 2 Diabetes, Urinary Tract Infections | DAPAGLIFLOZIN, EMPAGLIFLOZIN, LINAGLIPTIN, SAXAGLIPTIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT02555059 | Special Drug Use Investigation of Ciproxan Injection in Pediatrics | 48 | Cystitis / Pyelonephritis / Cystic Fibrosis / Anthrax | CIPROFLOXACIN | Its record names the disease | ClinicalTrials.gov | ||
| NCT03174795 | A Study to Investigate the Pharmacokinetics of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection | Phase 1 | 20 | Urinary Tract Infections | MEROPENEM, NACUBACTAM | Its record names the disease | ClinicalTrials.gov | |
| NCT06128213 | NRX-101 for Complicated Urinary Tract Infection (UTI) Including Pyelonephritis | Phase 2 | 13 | Urinary Tract Infections, Pyelonephritis | CYCLOSERINE, LURASIDONE | Its record names the disease | ClinicalTrials.gov | |
| NCT01820793 | Efficacy and Pharmacokinetic/Pharmacodynamic Parameters of Cefoxitin in Women With Acute Pyelonephritis Without Severity Symptoms Due to Extended-spectrum β-lactamase Producing Escherichia Coli | Not applicable | 9 | Acute Pyelonephritis Without Severity Symptoms Due to ESBL-producing E.Coli | CEFOXITIN | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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