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Disease · MONDO_0007959

Comparisons in its trials17

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Average-Risk Group vs High-Risk Group: serious adverse events17 of 26917 of 144413NCT00085202Trial comparisons
Arm I (Temozolomide, Irinotecan Hydrochloride) vs Arm II (Temozolomide, Irinotecan Hydrochloride, Bevacizumab): deaths from any cause48 of 5442 of 52106NCT01217437Trial comparisons
Arm I (Temozolomide, Irinotecan Hydrochloride) vs Arm II (Temozolomide, Irinotecan Hydrochloride, Bevacizumab): serious adverse events9 of 5412 of 52106NCT01217437Trial comparisons
Temozolomide + Irinotecan for Medulloblastoma vs Temozolomide + Irinotecan for High-Grade Glioma: serious adverse events31 of 665 of 1783NCT00404495Trial comparisons
Arm I (Patients Treated Without Methotrexate (MTX)) vs Arm II (Patients Treated With MTX): Number of Participants With Chronic Primary Hypothyroidism/Subclinical Compensatory HypothyroidismHypothyroidism/Subclinical Compensatory Hypothyroidism
3 of 395 of 3877NCT00336024Trial comparisons
Arm I (Patients Treated Without Methotrexate (MTX)) vs Arm II (Patients Treated With MTX): Number of Participants With Chronic Low Somatomedin C2 of 395 of 3877NCT00336024Trial comparisons
Arm I (Patients Treated Without Methotrexate (MTX)) vs Arm II (Patients Treated With MTX): Number of Participants With Secondary Malignancies1 of 390 of 3877NCT00336024Trial comparisons
Arm I (Patients Treated Without Methotrexate (MTX)) vs Arm II (Patients Treated With MTX): Number of Participants With Chronic Diabetes Insipidus1 of 391 of 3877NCT00336024Trial comparisons
Arm I (Patients Treated Without Methotrexate (MTX)) vs Arm II (Patients Treated With MTX): deaths from any cause18 of 3915 of 3877NCT00336024Trial comparisons
Arm I (Patients Treated Without Methotrexate (MTX)) vs Arm II (Patients Treated With MTX): Number of Participants With Chronic Central Hypothyroidism1 of 391 of 3877NCT00336024Trial comparisons
Arm I (Patients Treated Without Methotrexate (MTX)) vs Arm II (Patients Treated With MTX): serious adverse events8 of 393 of 3877NCT00336024Trial comparisons
Intermediate-Risk Group vs High-Risk Group: Participants With PK-guided Dosage Adjustment Achieving Target System Exposure of Intravenous Topotecan1 of 120 of 2728NCT00602667Trial comparisons
Intermediate-Risk Group vs High-Risk Group: Participants With Empirical Dosage Achieving Target System Exposure of Intravenous Topotecan0 of 18 of 2728NCT00602667Trial comparisons
Dose Level 1 vs Dose Level 2: serious adverse events1 of 61 of 612NCT00993044Trial comparisons
10 mCi 177Lu-DTPA-omburtamab vs 25 mCi 177Lu-DTPA-omburtamab: Dose Limiting Toxicities (DLTs) Part 10 of 11 of 12NCT04167618Trial comparisons
10 mCi 177Lu-DTPA-omburtamab vs 25 mCi 177Lu-DTPA-omburtamab: deaths from any cause0 of 10 of 12NCT04167618Trial comparisons
10 mCi 177Lu-DTPA-omburtamab vs 25 mCi 177Lu-DTPA-omburtamab: serious adverse events1 of 10 of 12NCT04167618Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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