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Disease · MONDO_0009757

Comparisons in its trials11

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Adrabetadex vs Sham Control: Parts A/B: Number of Participants Treated for at Least 6 Months Who Qualified for the Rescue Option2 of 382 of 1856NCT02534844Trial comparisons
Adrabetadex vs Sham Control: Parts A/ B: Number of Participants Classified as CGIC Responders at Week 5223 of 387 of 1856NCT02534844Trial comparisons
Adrabetadex vs Sham Control: Parts A/B: Number of Participants Classified as Responders on NPC-SS Total Score (Excluding Hearing and ABR) at Week 5222 of 3813 of 1856NCT02534844Trial comparisons
VTS-270 at 500 mg/kg vs VTS-270 at 1000 mg/kg: Participants With Reduction in Liver Stiffness (kPa)0 of 10 of 12NCT03887533Trial comparisons
VTS-270 at 500 mg/kg vs VTS-270 at 1000 mg/kg: Participants With Reduction in Plasma Bile Acid B (5α)1 of 10 of 12NCT03887533Trial comparisons
VTS-270 at 500 mg/kg vs VTS-270 at 1000 mg/kg: Participants With Reduction in Aspartate Aminotransferase1 of 11 of 12NCT03887533Trial comparisons
VTS-270 at 500 mg/kg vs VTS-270 at 1000 mg/kg: Participants With Reduction in Plasma Cholestane-3β1 of 10 of 12NCT03887533Trial comparisons
VTS-270 at 500 mg/kg vs VTS-270 at 1000 mg/kg: Participants With Reduction in C-Triol (6β-triol)1 of 10 of 12NCT03887533Trial comparisons
VTS-270 at 500 mg/kg vs VTS-270 at 1000 mg/kg: Participants With Reduction in Alanine Aminotransferase Level0 of 10 of 12NCT03887533Trial comparisons
VTS-270 at 500 mg/kg vs VTS-270 at 1000 mg/kg: deaths from any cause0 of 10 of 12NCT03887533Trial comparisons
VTS-270 at 500 mg/kg vs VTS-270 at 1000 mg/kg: serious adverse events1 of 10 of 12NCT03887533Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0009757/comparisons