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Disease · MONDO_0010030

Comparisons in its trials22

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Arm 1: Iscalimab 600 mg vs Arm 2 - Iscalimab 300 mg: Incidence of Anti-iscalimab Antibodies in Plasma1 of 1522 of 54206NCT04541589Trial comparisons
Arm 1: Iscalimab 600 mg vs Arm 2 - Iscalimab 300 mg: deaths from any cause0 of 1520 of 54206NCT04541589Trial comparisons
Arm 1: Iscalimab 600 mg vs Arm 2 - Iscalimab 300 mg: serious adverse events13 of 1522 of 54206NCT04541589Trial comparisons
Population 2: VIB4920 vs Population 2: Placebo: Population 2: Number of Participants Who Achieved ESSPRI Response at Day 16936 of 5418 of 55109NCT04129164Trial comparisons
SAR441344 vs Placebo: deaths from any cause0 of 420 of 4284NCT04572841Trial comparisons
SAR441344 vs Placebo: serious adverse events1 of 421 of 4284NCT04572841Trial comparisons
Baminercept 100 mg vs Placebo: serious adverse events5 of 331 of 1952NCT01552681Trial comparisons
DNase vs Vehicle: deaths from any cause0 of 250 of 2247NCT02193490Trial comparisons
DNase vs Vehicle: serious adverse events0 of 250 of 2247NCT02193490Trial comparisons
Any MEDI5872 210 mg vs Placebo: Number of Participants With Adverse Events of Special Interest (AESIs)6 of 311 of 1647NCT02334306Trial comparisons
Any MEDI5872 210 mg vs Placebo: deaths from any cause0 of 310 of 1647NCT02334306Trial comparisons
Any MEDI5872 210 mg vs Placebo: serious adverse events1 of 310 of 1647NCT02334306Trial comparisons
Efgartigimod vs Placebo: deaths from any cause0 of 230 of 1134NCT05817669Trial comparisons
Efgartigimod vs Placebo: serious adverse events1 of 230 of 1134NCT05817669Trial comparisons
CDZ173 vs Placebo: deaths from any cause0 of 200 of 1030NCT02775916Trial comparisons
CDZ173 vs Placebo: serious adverse events1 of 200 of 1030NCT02775916Trial comparisons
Efgartigimod-Efgartigimod vs Placebo-Efgartigimod: Number of Participants With ADA Against Efgartigimod Over the 48-week Treatment Period6 of 174 of 724NCT06203457Trial comparisons
Efgartigimod-Efgartigimod vs Placebo-Efgartigimod: deaths from any cause0 of 170 of 724NCT06203457Trial comparisons
Efgartigimod-Efgartigimod vs Placebo-Efgartigimod: serious adverse events0 of 172 of 724NCT06203457Trial comparisons
Raptiva vs Placebo: serious adverse events0 of 80 of 311NCT00344448Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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