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Disease · MONDO_0010526

Comparisons in its trials11

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Lucerastat vs Placebo: deaths from any cause0 of 800 of 37117NCT03425539Trial comparisons
Lucerastat vs Placebo: serious adverse events5 of 801 of 37117NCT03425539Trial comparisons
PRX-102 (Pegunigalsidase Alfa) vs Agalsidase Beta: deaths from any cause0 of 520 of 2577NCT02795676Trial comparisons
PRX-102 (Pegunigalsidase Alfa) vs Agalsidase Beta: serious adverse events8 of 526 of 2577NCT02795676Trial comparisons
Lead-in Period (Fabrazyme) vs Treatment Period (AGA BETA BS): deaths from any cause0 of 200 of 1939NCT05843916Trial comparisons
Lead-in Period (Fabrazyme) vs Treatment Period (AGA BETA BS): serious adverse events0 of 205 of 1939NCT05843916Trial comparisons
Fabrazyme 0.5 mg/kg vs Fabrazyme 1.0 mg/kg: serious adverse events6 of 165 of 1531NCT00701415Trial comparisons
Safety Population RB vs Transition Safety Population: serious adverse events2 of 172 of 1128NCT00084084Trial comparisons
Pegunigalsidase Alfa Reporting Group vs Phenotypically Classic Fabry Patients: Gastrointestinal Symptoms Questionnaire - Severity of Abdominal Pain10 of 167 of 1026NCT01678898Trial comparisons
Pegunigalsidase Alfa Reporting Group vs Phenotypically Classic Fabry Patients: Gastrointestinal Symptoms Questionnaire - Frequency of Abdominal Pain7 of 165 of 1026NCT01678898Trial comparisons
Pegunigalsidase Alfa Reporting Group vs Phenotypically Classic Fabry Patients: Gastrointestinal Symptoms Questionnaire - Frequency of Diarrhea11 of 166 of 1026NCT01678898Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

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