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Disease · MONDO_0016532

Comparisons in its trials16

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Dravet Syndrome vs Lennox-Gastaut Syndrome: deaths from any cause6 of 31512 of 366681NCT02224573Trial comparisons
Dravet Syndrome vs Lennox-Gastaut Syndrome: serious adverse events133 of 315157 of 366681NCT02224573Trial comparisons
Soticlestat vs Placebo: deaths from any cause0 of 1340 of 136270NCT04938427Trial comparisons
Soticlestat vs Placebo: serious adverse events11 of 13410 of 136270NCT04938427Trial comparisons
GWP42003-P 20 mg/kg/Day Dose vs Placebo: Number Of Participants With a ≥50% Reduction From Baseline in Drop Seizure Frequency During The Treatment Period38 of 8620 of 85171NCT02224690Trial comparisons
GWP42003-P 20 mg/kg/Day Dose vs Placebo: serious adverse events20 of 864 of 85171NCT02224690Trial comparisons
TAK-935 vs Placebo: deaths from any cause0 of 710 of 70141NCT03650452Trial comparisons
TAK-935 vs Placebo: serious adverse events11 of 7113 of 70141NCT03650452Trial comparisons
Clobazam Low Dose vs Clobazam High Dose: serious adverse events1 of 323 of 3668NCT00162981Trial comparisons
Rufinamide (E2080) vs Placebo: serious adverse events1 of 291 of 3059NCT01146951Trial comparisons
Rufinamide vs Any Other Approved Antiepileptic Drug: deaths from any cause1 of 250 of 1237NCT01405053Trial comparisons
Rufinamide vs Any Other Approved Antiepileptic Drug: serious adverse events10 of 255 of 1237NCT01405053Trial comparisons
Tuberous Sclerosis Complex vs Dravet Syndrome: Number of Participants With Treatment-Emergent Adverse Events (TEAEs)2 of 21 of 13NCT04485104Trial comparisons
Tuberous Sclerosis Complex vs Dravet Syndrome: deaths from any cause0 of 20 of 13NCT04485104Trial comparisons
Tuberous Sclerosis Complex vs Dravet Syndrome: Number of Participants With Emergence of New Types of Seizures1 of 20 of 13NCT04485104Trial comparisons
Tuberous Sclerosis Complex vs Dravet Syndrome: serious adverse events2 of 20 of 13NCT04485104Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0016532/comparisons