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Disease · MONDO_0017844

Trials51

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT01728805Study of KW-0761 Versus Vorinostat in Relapsed/Refractory CTCLPhase 33722019-04-11Cutaneous T-Cell LymphomaMOGAMULIZUMAB, VORINOSTATIts record names the diseaseClinicalTrials.gov
NCT02663518A Trial of PF-07901800 (TTI-621) for Patients With Hematologic Malignancies and Selected Solid TumorsPhase 12492024-05-10Hematologic Malignancies, Solid TumorNIVOLUMAB, RITUXIMABIts record names the diseaseClinicalTrials.gov
NCT00425555Study of Oral LBH589 in Adult Patients With Refractory Cutaneous T-Cell LymphomaPhase 21392021-08-16Cutaneous T-Cell LymphomaPANOBINOSTATIts record names the diseaseClinicalTrials.gov
NCT03493451Study of BGB-A317 in Participants With Relapsed or Refractory Mature T- and NK-cell NeoplasmsPhase 2772022-05-04
Peripheral T Cell Lymphoma, PTCL, Extranodal NK/T-cell Lymphoma, Extranodal NK/T-cell Lymphoma, Nasal Type, Extranodal NK T Cell Lymphoma, Extranodal NK T Cell Lymphoma, Nasal, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Angioimmunoblastic T-Cell Lymphoma Recurrent, Angioimmunoblastic T-Cell Lymphoma Refractory, Peripheral T-cell Lymphoma NOS, Peripheral T-Cell Lymphoma, Not Otherwise Specified, Peripheral T-Cell Lymphoma Refractory, Anaplastic Large Cell Lymphoma, Anaplastic Large Cell Lymphoma, ALK-Positive, Anaplastic Large Cell Lymphoma, ALK-negative, ALK-negative Anaplastic Large Cell Lymphoma, ALK-Positive Anaplastic Large Cell Lymphoma, Cutaneous T-cell Lymphoma
TISLELIZUMABIts record names the diseaseClinicalTrials.gov
NCT00896493Ph II of Non-myeloablative Allogeneic Transplantation Using TLI & ATG In Patients w/ Cutaneous T Cell LymphomaPhase 2382023-05-11Mycoses, Sezary Syndrome, Lymphoma, T-Cell, Cutaneous, Bone Marrow Transplant Failure, Lymphoma, Non-Hodgkin, Cutaneous T-cell LymphomaCYCLOSPORINEIts record names the diseaseClinicalTrials.gov
NCT01396070Brentuximab Vedotin (SGN-35) in Patients With Mycosis Fungoides With Variable CD30 Expression LevelPhase 2362017-04-05Non-Hodgkin Lymphoma (NHL), Cutaneous Lymphoma, Cutaneous T-cell Lymphoma (CTCL), Mycosis Fungoides, Sezary SyndromeBRENTUXIMAB VEDOTINIts record names the diseaseClinicalTrials.gov
NCT00466921Lenalidomide in Treating Patients With Relapsed Mycosis Fungoides/Sezary SyndromePhase 2332020-11-16LymphomaLENALIDOMIDEIts record names the diseaseClinicalTrials.gov
NCT03063632Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial SarcomaPhase 2282022-08-30
Metastatic Myxoid Liposarcoma, Metastatic Round Cell Liposarcoma, Metastatic Synovial Sarcoma, Recurrent Mycosis Fungoides and Sezary Syndrome, Refractory Mycosis Fungoides and Sezary Syndrome, Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage II Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage III Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIIA Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIIB Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IVA Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IVB Mycosis Fungoides and Sezary Syndrome AJCC v7, Unresectable Synovial Sarcoma
INTERFERON GAMMA-1B, PEMBROLIZUMABIts record names the diseaseClinicalTrials.gov
NCT00907738A Continuation Clinical Trial of Oral Vorinostat (MK-0683) in Advanced Cancers (MK-0683-007)Phase 2272011-07-14Advanced CancerVORINOSTATIts record names the diseaseClinicalTrials.gov
NCT00744991A Study for Participants With Relapsed Cutaneous T-Cell LymphomaPhase 2252020-10-19Cutaneous T-Cell LymphomaENZASTAURINIts record names the diseaseClinicalTrials.gov
NCT02243579Pembrolizumab in Treating Patients With Relapsed or Refractory Stage IB-IVB Mycosis Fungoides or Sezary SyndromePhase 2242019-02-05
Recurrent Mycosis Fungoides and Sezary Syndrome, Refractory Mycosis Fungoides and Sezary Syndrome, Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIIA Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIIB Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IVA Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IVB Mycosis Fungoides and Sezary Syndrome AJCC v7
PEMBROLIZUMABIts record names the diseaseClinicalTrials.gov
NCT00369629Gemcitabine and Pemetrexed Disodium in Treating Patients With Advanced Mycosis Fungoides or Sézary SyndromePhase 1142018-10-09LymphomaGEMCITABINE, PEMETREXEDIts record names the diseaseClinicalTrials.gov
NCT04541017
Testing the Addition of an Anti-cancer Drug, Hu5F9-G4 (Magrolimab), to the Usual Chemotherapy Treatment (Mogamulizumab) in T-Cell (a Type of Immune Cell) Lymphoma That Has Returned After Treatment or Does Not Respond to Treatment
Phase 1/282025-10-16
Mycosis Fungoides, Recurrent Mycosis Fungoides, Recurrent Mycosis Fungoides and Sezary Syndrome, Recurrent Sezary Syndrome, Refractory Mycosis Fungoides, Refractory Mycosis Fungoides and Sezary Syndrome, Refractory Sezary Syndrome, Sezary Syndrome, Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v8, Stage II Mycosis Fungoides and Sezary Syndrome AJCC v8, Stage III Mycosis Fungoides and Sezary Syndrome AJCC v8, Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v8
MAGROLIMAB, MOGAMULIZUMABIts record names the diseaseClinicalTrials.gov
NCT00724061Study of Pegylated Interferon-Alfa 2b in Combination With PUVA Therapy In CTCLNot applicable72013-12-02LymphomaINTERFERON ALFA-2B, PSORALENIts record names the diseaseClinicalTrials.gov
NCT04185220Phase I Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for People With Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary SyndromePhase 162021-12-14Adult T-Cell Lymphoma/Leukemia, Sezary Syndrome, Mycosis FungoidesINTERLEUKIN 15, RECOMBINANT NON-GLYCOSYLATED, MOGAMULIZUMABIts record names the diseaseClinicalTrials.gov
NCT00047060Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary SyndromePhase 1/252020-02-24Mycosis Fungoides, Sezary SyndromeALEMTUZUMAB, CYCLOPHOSPHAMIDE, FLUDARABINEIts record names the diseaseClinicalTrials.gov
NCT01226472Extension Study in Subjects Who Relapsed After Complete Response on Study KW-0761-001Phase 212020-12-29Peripheral T-cell Lymphoma, Cutaneous T-cell LymphomaMOGAMULIZUMABIts record names the diseaseClinicalTrials.gov
NCT03902184IPH4102/Lacutamab Alone or in Combination With Chemotherapy in Patients With Advanced T Cell LymphomaPhase 2170Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Mycosis Fungoides/Sezary SyndromeLACUTAMABIts record names the diseaseClinicalTrials.gov
NCT04858256Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative NeoplasmsPhase 2100T-Cell Neoplasm, Lymphoproliferative DisordersPACRITINIBIts record names the diseaseClinicalTrials.gov
NCT00127881Study of Human Monoclonal Antibody to Treat Mycosis Fungoides and Sezary SyndromePhase 376Mycosis Fungoides, Sezary SyndromeZANOLIMUMABIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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