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Disease · MONDO_0018078

Comparisons in its trials59

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Doxorubicin + Olaratumab vs Doxorubicin + Placebo: deaths from any cause170 of 257158 of 249506NCT02451943Trial comparisons
Doxorubicin + Olaratumab vs Doxorubicin + Placebo: serious adverse events105 of 25789 of 249506NCT02451943Trial comparisons
Aldoxorubicin vs Investigator's Choice of Treatment: deaths from any cause148 of 213131 of 207420NCT02049905Trial comparisons
Aldoxorubicin vs Investigator's Choice of Treatment: serious adverse events91 of 21368 of 207420NCT02049905Trial comparisons
Pazopanib vs Placebo: serious adverse events99 of 24029 of 123363NCT00753688Trial comparisons
Part 2: MORAb-004 8.0 mg/kg + Gemcitabine/Docetaxel vs Part 2: Placebo + Gemcitabine/Docetaxel: Part 2: Number of Participants Who Had Relationship Between MORAb-004 Exposures and Biomarker Levels0 of 1390 of 70209NCT01574716Trial comparisons
PDR001+LAG525 On-treatment Period vs PDR001+LAG525 Extended Safety Follow-up Period: deaths from any cause9 of 7618 of 76152NCT03365791Trial comparisons
PDR001+LAG525 On-treatment Period vs PDR001+LAG525 Extended Safety Follow-up Period: serious adverse events31 of 764 of 76152NCT03365791Trial comparisons
Doxorubicin vs INNO-206: Number of Participants With Treatment-related Toxicities (Adverse Events)29 of 4075 of 83123NCT01514188Trial comparisons
Doxorubicin vs INNO-206: deaths from any cause26 of 4040 of 83123NCT01514188Trial comparisons
Doxorubicin vs INNO-206: serious adverse events8 of 4033 of 83123NCT01514188Trial comparisons
Phase 2: Olaratumab + Gemcitabine + Docetaxel (Olaratumab-naive) vs Phase 2: Olaratumab + Gemcitabine + Docetaxel (Olaratumab Pre-treated): Phase 2: Number of Participants With Treatment Emergent Anti-Olaratumab Antibodies
0 of 770 of 43120NCT02659020Trial comparisons
8 mg/kg TRC105 + Pazopanib vs 10 mg/kg TRC105 + Pazopanib: deaths from any cause0 of 39 of 106109NCT01975519Trial comparisons
8 mg/kg TRC105 + Pazopanib vs 10 mg/kg TRC105 + Pazopanib: serious adverse events0 of 39 of 106109NCT01975519Trial comparisons
LY573636 Target Cmax 420 µg/mL vs LY573636 Target Cmax 360 µg/mL: serious adverse events23 of 6310 of 38101NCT00490451Trial comparisons
SHR-1210 Plus Apatinib vs ADM Plus IFO or IFO Alone: Objective Response Rate (ORR)11 of 505 of 4797NCT03711279Trial comparisons
SHR-1210 Plus Apatinib vs ADM Plus IFO or IFO Alone: deaths from any cause2 of 502 of 4797NCT03711279Trial comparisons
SHR-1210 Plus Apatinib vs ADM Plus IFO or IFO Alone: serious adverse events27 of 5013 of 4797NCT03711279Trial comparisons
Experimental vs Standard of Care: Rate of Participants With Grade 3 or Higher Toxicity39 of 4539 of 4590NCT01593748Trial comparisons
Experimental vs Standard of Care: deaths from any cause32 of 4530 of 4590NCT01593748Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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