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Disease · MONDO_0018646

Comparisons in its trials18

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Ursodeoxycholic Acid vs Placebo: Number of Participants Who Developed Varices15 of 765 of 74150NCT00059202Trial comparisons
Ursodeoxycholic Acid vs Placebo: Number of Participants With Treatment Failure30 of 7619 of 74150NCT00059202Trial comparisons
Ursodeoxycholic Acid vs Placebo: Number of Deaths5 of 763 of 74150NCT00059202Trial comparisons
Ursodeoxycholic Acid vs Placebo: Number of Participants Meeting Minimal Listing Criteria for Liver Transplantation13 of 7610 of 74150NCT00059202Trial comparisons
Ursodeoxycholic Acid vs Placebo: Number of Participants Who Developed Cholangiocarcinoma2 of 762 of 74150NCT00059202Trial comparisons
Ursodeoxycholic Acid vs Placebo: Number of Participants Who Developed Cirrhosis6 of 764 of 74150NCT00059202Trial comparisons
Ursodeoxycholic Acid vs Placebo: deaths from any cause5 of 763 of 74150NCT00059202Trial comparisons
Ursodeoxycholic Acid vs Placebo: Number of Participants Who Have a Liver Transplantation11 of 765 of 74150NCT00059202Trial comparisons
Ursodeoxycholic Acid vs Placebo: serious adverse events0 of 760 of 74150NCT00059202Trial comparisons
Oral Vancomycin-Children vs Oral Vancomycin-Adults: deaths from any cause0 of 140 of 2034NCT01802073Trial comparisons
Oral Vancomycin-Children vs Oral Vancomycin-Adults: serious adverse events1 of 140 of 2034NCT01802073Trial comparisons
Oral Vancomycin-Children vs Oral Vancomycin-Adults: Count of Participants With Elevated ALT and/or GGT at Baseline and With Clinically Significant Improvement at Month 310 of 108 of 1020NCT01802073Trial comparisons
Oral Vancomycin-Children vs Oral Vancomycin-Adults: Count of Participants With Elevated Alanine Aminotransferase (ALT) at Baseline and With Clinically Significant Improvement at Month 310 of 106 of 919NCT01802073Trial comparisons
Oral Vancomycin-Children vs Oral Vancomycin-Adults: Count of Participants With Abnormal MRCP and/or Liver Biopsy at Baseline and With Clinically Significant Improvement at Year 110 of 104 of 919NCT01802073Trial comparisons
Oral Vancomycin-Children vs Oral Vancomycin-Adults: Count of Participants With Elevated Gamma-glutamyltransferase (GGT) at Baseline and With Clinically Significant Improvement at Month 38 of 86 of 917NCT01802073Trial comparisons
Oral Vancomycin-Children vs Oral Vancomycin-Adults: Count of Participants With Abnormal Magnetic Resonance Cholangiopancreatography (MRCP) Imaging at Baseline and With Clinically Significant Improvement at Year 1
6 of 84 of 816NCT01802073Trial comparisons
DUR-928 10 mg vs DUR-928 50 mg: deaths from any cause0 of 30 of 25NCT03394781Trial comparisons
DUR-928 10 mg vs DUR-928 50 mg: serious adverse events0 of 30 of 25NCT03394781Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0018646/comparisons