Disease · MONDO_0021040
Trials753
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 29 more are not shown, since the checks do not confirm them.
1 to 20 of 753
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00940225 | Study of Cabozantinib (XL184) in Adults With Advanced Malignancies | Phase 2 | 730 | 2024-04-25 | Solid Tumors, Cancer | CABOZANTINIB | Its record names the disease | ClinicalTrials.gov |
| NCT00471146 | Study Of Gemcitabine Plus AG-013736 Versus Gemcitabine For Advanced Pancreatic Cancer. | Phase 3 | 630 | 2012-07-16 | Carcinoma, Pancreatic Ductal | AXITINIB, GEMCITABINE | Its record names the disease | ClinicalTrials.gov |
| NCT00574275 | Aflibercept Compared to Placebo in Term of Efficacy in Patients Treated With Gemcitabine for Metastatic Pancreatic Cancer | Phase 3 | 546 | 2012-09-25 | Pancreatic Neoplasm | AFLIBERCEPT, GEMCITABINE | Its record names the disease | ClinicalTrials.gov |
| NCT01013649 | Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery | Phase 3 | 546 | 2024-10-24 | Pancreatic Adenocarcinoma, Pancreatic Ductal Adenocarcinoma, Pancreatic Intraductal Papillary-Mucinous Neoplasm, Stage I Pancreatic Cancer AJCC v6 and v7, Stage II Pancreatic Cancer AJCC v6 and v7 | CAPECITABINE, ERLOTINIB HYDROCHLORIDE, FLUOROURACIL, GEMCITABINE HYDROCHLORIDE | Its record names the disease | ClinicalTrials.gov |
| NCT01631552 | Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer | Phase 1/2 | 515 | 2021-04-06 | Gastric Adenocarcinoma, Esophageal Cancer, Hepatocellular Carcinoma, Non-small Cell Lung Cancer, Small Cell Lung Cancer, Ovarian Epithelial Cancer, Carcinoma Breast Stage IV, Hormone-refractory Prostate Cancer, Head and Neck Cancers- Squamous Cell, Renal Cell Cancer, Urinary Bladder Neoplasms, Cervical Cancer, Endometrial Cancer, Glioblastoma Multiforme, Triple Negative Breast Cancer, Pancreatic Cancer | SACITUZUMAB GOVITECAN | Its record names the disease | ClinicalTrials.gov |
| NCT03665441 | Study of Eryaspase in Combination With Chemotherapy Versus Chemotherapy Alone as 2nd-Line Treatment in PAC | Phase 3 | 512 | 2022-09-28 | Pancreatic Adenocarcinoma | ASPARAGINASE, FLUOROURACIL, GEMCITABINE, IRINOTECAN, IRINOTECAN HYDROCHLORIDE, LEUCOVORIN, PACLITAXEL | Its record names the disease | ClinicalTrials.gov |
| NCT01494506 | Study of MM-398 With or Without 5-FU/LV, Versus 5-FU/LV in Patients With Metastatic Pancreatic Cancer | Phase 3 | 417 | 2016-02-12 | Metastatic Pancreatic Cancer | FLUOROURACIL, IRINOTECAN, LEUCOVORIN CALCIUM | Its record names the disease | ClinicalTrials.gov |
| NCT01124786 | A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP) | Phase 2 | 367 | 2014-04-17 | Metastatic Pancreatic Adenocarcinoma | GEMCITABINE, GEMCITABINE ELAIDATE | Its record names the disease | ClinicalTrials.gov |
| NCT02004262 | Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting | Phase 2 | 303 | 2018-05-03 | 2nd-line, 3rd-line and Greater Metastatic Pancreatic Cancer | CYCLOPHOSPHAMIDE | Its record names the disease | ClinicalTrials.gov |
| NCT03941093 | Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced, Unresectable Pancreatic Cancer | Phase 3 | 284 | 2024-11-05 | Pancreatic Cancer Non-resectable | FLUOROURACIL, GEMCITABINE, IRINOTECAN, LEUCOVORIN, OXALIPLATIN, PACLITAXEL, PAMREVLUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT02352337 | First-line Metastatic Pancreatic Cancer : FOLFIRINOX +/- LV5FU2 in Maintenance Versus Firgem | Phase 2 | 276 | 2024-07-10 | Metastatic Pancreatic Cancer | FLUOROURACIL, GEMCITABINE, IRINOTECAN, LEUCOVORIN, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT01647828 | A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Nab-Paclitaxel and Gemcitabine in Subjects With Previously Untreated Stage IV Pancreatic Cancer | Phase 1/2 | 217 | 2023-02-15 | Stage IV Pancreatic Cancer | GEMCITABINE, PACLITAXEL, TAREXTUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT03733990 | A Study to Evaluate Safety, Tolerability and Preliminary Efficacy of FP-1305 in Cancer Patients (MATINS) | Phase 1/2 | 216 | 2025-04-02 | Cancer | BEXMARILIMAB | Its record names the disease | ClinicalTrials.gov |
| NCT03336216 | A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer | Phase 2 | 205 | 2024-07-23 | Advanced Pancreatic Cancer | CABIRALIZUMAB, NIVOLUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT03565991 | Javelin BRCA/ATM: Avelumab Plus Talazoparib in Patients With BRCA or ATM Mutant Solid Tumors | Phase 2 | 202 | 2023-08-07 | Locally Advanced or Metastatic Solid Tumors, Genes, BRCA 1 | AVELUMAB, TALAZOPARIB | Its record names the disease | ClinicalTrials.gov |
| NCT03086369 | A Study of Nab-Paclitaxel and Gemcitabine With or Without Olaratumab (LY3012207) in Participants With Metastatic Pancreatic Cancer | Phase 1/2 | 184 | 2022-01-11 | Metastatic Pancreatic Cancer | GEMCITABINE, OLARATUMAB, PACLITAXEL | Its record names the disease | ClinicalTrials.gov |
| NCT03217747 | Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies | Phase 1/2 | 173 | 2025-10-14 | Advanced Malignant Solid Neoplasm, Castration-Resistant Prostate Carcinoma, Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Metastatic Prostate Carcinoma, Prostate Carcinoma Metastatic in the Bone, Refractory Malignant Solid Neoplasm, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8 | AVELUMAB, IVUXOLIMAB, UTOMILUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT01231581 | Study of GSK1120212 Plus Gemcitabine vs Placebo Plus Gemcitabine in Metastatic Pancreatic Cancer | Phase 2 | 160 | 2013-09-26 | Cancer | GEMCITABINE, TRAMETINIB | Its record names the disease | ClinicalTrials.gov |
| NCT00839332 | A Study for Participants With Pancreatic Cancer | Phase 1/2 | 157 | 2018-04-17 | Pancreatic Neoplasms | GEMCITABINE, RABUSERTIB | Its record names the disease | ClinicalTrials.gov |
| NCT02184195 | Olaparib in gBRCA Mutated Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum-Based Chemotherapy | Phase 3 | 154 | 2020-01-27 | Germline BRCA1/2 Mutations and, Metastatic Adenocarcinoma of the Pancreas | OLAPARIB | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0021040/trials