Disease · MONDO_0021071
Trials19
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.
1 to 19 of 19
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04030455 | Cisplatin, Docetaxel, and Pembrolizumab in Treating Patients With Stage II-III Laryngeal Cancer | Phase 2 | 28 | 2026-02-17 | Laryngeal Squamous Cell Carcinoma, Stage II Laryngeal Cancer AJCC v8, Stage III Laryngeal Cancer AJCC v8 | CISPLATIN, DOCETAXEL, PEMBROLIZUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT03894891 | Induction TPN Followed by Nivolumab With Radiation in Locoregionally Advanced Laryngeal and Hypopharyngeal Cancer | Phase 2 | 6 | 2023-12-20 | Head and Neck Cancer | CISPLATIN, DOCETAXEL, NIVOLUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT00599131 | Cetuximab and Radiation Therapy in Laryngeal Cancer Patients Who Have Responded to One Cycle of Chemotherapy (SPORE) | Phase 2 | 4 | 2014-06-16 | Cancer of Larynx | CETUXIMAB, CISPLATIN, DOCETAXEL, FLUOROURACIL | Its record names the disease | ClinicalTrials.gov |
| NCT00002839 | Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx | Phase 3 | 564 | Head and Neck Cancer | CISPLATIN, FLUOROURACIL | Its record names the disease | ClinicalTrials.gov | |
| NCT03340896 | Trial of Laryngeal Preservation Comparing Induced CT Followed by RT vs CT Concomitant to RT | Phase 3 | 256 | Head and Neck Squamous Cell Carcinoma | CISPLATIN, DOCETAXEL, FLUOROURACIL | Its record names the disease | ClinicalTrials.gov | |
| NCT00534729 | Organ Preservation: Weekly Carboplatin & Taxol w/Concurrent RT for Locally Advanced Laryngeal & Hypopharyngeal CA | Not applicable | 200 | Laryngeal Neoplasms, Hypopharyngeal Neoplasms | CARBOPLATIN, PACLITAXEL | Its record names the disease | ClinicalTrials.gov | |
| NCT00508664 | Docetaxel, Cisplatin (TP) + Radiation +/- Cetuximab in Larynx Carcinoma (CA) | Phase 2 | 180 | Squamous Cell Carcinoma of the Hypopharynx, Larynx Carcinoma | CETUXIMAB, CISPLATIN, DOCETAXEL, FLUOROURACIL | Its record names the disease | ClinicalTrials.gov | |
| NCT00169247 | Radiotherapy With Cisplatin Versus Radiotherapy With Cetuximab After Induction Chemotherapy for Larynx Preservation | Phase 2 | 156 | Larynx Cancer, Hypopharynx Cancer | CETUXIMAB, CISPLATIN | Its record names the disease | ClinicalTrials.gov | |
| NCT06000137 | The Comparison of the Analgesic Effects of Dezocine and Sufentanil in Patient-controlled Analgesia After Laryngectomy | Not applicable | 129 | Patient-controlled Analgesia | DEZOCINE, SUFENTANIL | Its record names the disease | ClinicalTrials.gov | |
| NCT01073683 | Induction Docetaxel/Cisplatin/5-fluorouracil (TPF) as Selector for Chemo Radiation Therapy (RT) Versus Partial Laryngectomy in Advanced Laryngeal Cancer | Phase 2 | 100 | Larynx Cancer | CISPLATIN, DOCETAXEL, FLUOROURACIL | Its record names the disease | ClinicalTrials.gov | |
| NCT07423078 | Window of Opportunity in Preserving Laryngeal Function Trial | Phase 2 | 87 | Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M), Locally Advanced Laryngeal Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma | CARBOPLATIN, CISPLATIN, PACLITAXEL, TORIPALIMAB | Its record names the disease | ClinicalTrials.gov | |
| NCT06039631 | Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer | Phase 2 | 82 | Larynx Cancer, Hypopharyngeal Cancer | TORIPALIMAB | Its record names the disease | ClinicalTrials.gov | |
| NCT04510337 | Does Adding Magnesium Sulphate to Low Dose Rocuronium Affects Depth of Blockade | Not applicable | 60 | Anesthesia | MAGNESIUM SULFATE, ROCURONIUM | Open Targets' reading of its record | ClinicalTrials.gov | |
| NCT06554028 | Tislelizumab and Induction Chemotherapy for Larynx Preservation in Resectable Advanced Laryngeal/Hypopharyngeal Cancer | Phase 2 | 46 | Laryngeal Cancer, Hypopharynx Cancer, Laryngeal Neoplasms | TISLELIZUMAB | Its record names the disease | ClinicalTrials.gov | |
| NCT02849314 | Combination of Cryosurgey and NK Immunotherapy for Recurrent Laryngeal Cancer | Phase 1/2 | 30 | Recurrent Laryngeal Cancer | TROCULEUCEL | Its record names the disease | ClinicalTrials.gov | |
| NCT02048020 | Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer | Phase 2 | 26 | Human Papilloma Virus Infection, Stage III Squamous Cell Carcinoma of the Hypopharynx, Stage III Squamous Cell Carcinoma of the Larynx, Stage III Squamous Cell Carcinoma of the Oropharynx, Stage III Verrucous Carcinoma of the Larynx, Stage IV Squamous Cell Carcinoma of the Hypopharynx, Stage IV Verrucous Carcinoma of the Larynx, Stage IVA Squamous Cell Carcinoma of the Larynx, Stage IVA Squamous Cell Carcinoma of the Oropharynx, Stage IVA Verrucous Carcinoma of the Larynx, Stage IVB Squamous Cell Carcinoma of the Larynx, Stage IVB Squamous Cell Carcinoma of the Oropharynx, Stage IVB Verrucous Carcinoma of the Larynx, Stage IVC Squamous Cell Carcinoma of the Larynx, Stage IVC Squamous Cell Carcinoma of the Oropharynx, Stage IVC Verrucous Carcinoma of the Larynx | CARBOPLATIN, PACLITAXEL | Its record names the disease | ClinicalTrials.gov | |
| NCT05544136 | A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer | Phase 2 | 12 | Head and Neck Cancer, Head and Neck Carcinoma, Head and Neck Neoplasms, Head and Neck Squamous Cell Carcinoma | CARBOPLATIN | Its record names the disease | ClinicalTrials.gov | |
| NCT03028766 | WEE1 Inhibitor with Cisplatin and Radiotherapy: a Trial in Head and Neck Cancer | Phase 1 | 9 | Hypopharynx Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma, Larynx Cancer | ADAVOSERTIB, CISPLATIN | Its record names the disease | ClinicalTrials.gov | |
| NCT00004094 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Advanced Cancer of the Mouth, Pharynx, or Larynx | Phase 2 | Head and Neck Cancer | CARBOPLATIN, FLUOROURACIL, HYDROXYUREA, PACLITAXEL | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0021071/trials