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Disease · MONDO_0033821

Trials11

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT05110001Rose Bengal Electromagnetic Activation With Green Light for Infection ReductionPhase 33302026-01-30Acanthamoeba Keratitis, Fungal KeratitisCHLORHEXIDINE GLUCONATE, MOXIFLOXACIN, NATAMYCIN, ROSE BENGAL FREE ACIDIts record names the diseaseClinicalTrials.gov
NCT00996736Mycotic Ulcer Treatment Trial IPhase 33232013-12-11Corneal Ulcer, Eye Infections, FungalNATAMYCIN, VORICONAZOLEIts record names the diseaseClinicalTrials.gov
NCT02570321Cross-linking for Corneal Ulcers Treatment TrialPhase 31472024-08-27Corneal Ulcer, Infectious Keratitis, Bacterial Ulcer, Fungal UlcerAMPHOTERICIN B, MOXIFLOXACIN, NATAMYCINIts record names the diseaseClinicalTrials.gov
NCT02731638Mycotic Antimicrobial Localized Injection for Treatment of Corneal UlcersPhase 3702019-10-01Corneal Ulcer, Fungal KeratitisNATAMYCIN, VORICONAZOLEIts record names the diseaseClinicalTrials.gov
NCT06658002Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine APhase 3150Fungal Keratitis, Corneal UlcerCYCLOSPORINE, NATAMYCINIts record names the diseaseClinicalTrials.gov
NCT05655689The Antibiogram and Outcomes of Antimicrobial Regimens in Microbial Keratitis: A Prospective Cohort Study123Bacterial Keratitis, Fungal Keratitis, Mixed Bacterial and Fungal Keratitis, Microbial KeratitisCEFTAZIDIME, GENTAMICIN, MOXIFLOXACIN, NATAMYCIN, VANCOMYCIN, VORICONAZOLEIts record names the diseaseClinicalTrials.gov
NCT06463678Trial to Evaluate the Efficacy And Safety of IVIEW-1201 In the Treatment of Fungal KeratitisPhase 260Fungal KeratitisPOVIDONE-IODINEIts record names the diseaseClinicalTrials.gov
NCT03230058Combination Treatment of 5% Natamycin and 1% Voriconazole in Fungal KeratitisPhase 2/355Infection, FungalNATAMYCIN, VORICONAZOLEIts record names the diseaseClinicalTrials.gov
NCT07557966Intrastromal Injection of Fluconazole in Treatment of Fungal KeratitisNot applicable40Safety, Efficacy, Intrastromal Injection, Fluconazole, Treatment, Fungal KeratitisFLUCONAZOLEIts record names the diseaseClinicalTrials.gov
NCT03138785UVX as an Adjuvant in the Treatment of Fungal KeratitisNot applicable20TreatmentITRACONAZOLE, LEVOFLOXACIN, VORICONAZOLEIts record names the diseaseClinicalTrials.gov
NCT05489510PXL-Platinum 330 in Eyes With Corneal Thinning ConditionsPhase 1/20Corneal Thinning, KeratoconusRIBOFLAVINIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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