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Disease · MONDO_0043373

Trials16

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT00097448Sudden Deafness Treatment TrialPhase 32552013-04-04Sudden DeafnessMETHYLPREDNISOLONE SODIUM SUCCINATE, PREDNISONEIts record names the diseaseClinicalTrials.gov
NCT02809118Efficacy and Safety of AM-111 as Acute Sudden Sensorineural Hearing Loss TreatmentPhase 3562020-08-07Hearing Loss, Idiopathic Sudden SensorineuralBRIMAPITIDE, C-TERMINAL ACIDIts record names the diseaseClinicalTrials.gov
NCT02026479Sudden Hearing Loss Multi-center Clinical TrialNot applicable300Full-frequency Sudden Hearing LossDEXAMETHASONE PHOSPHORIC ACIDOpen Targets' reading of its recordClinicalTrials.gov
NCT02561091AM-111 in the Treatment of Acute Inner Ear Hearing LossPhase 3256Hearing LossBRIMAPITIDE, C-TERMINAL ACIDIts record names the diseaseClinicalTrials.gov
NCT07134075Intracochlear Injection of GlucocorticoidPhase 2150Sudden Sensorineural Hearing Loss (SSNHL)DEXAMETHASONE, TRIAMCINOLONE ACETONIDEIts record names the diseaseClinicalTrials.gov
NCT07113158Effect of Aspirin and Folic Acid for Sudden Sensorineural Hearing LossPhase 3142Sudden Sensorineural Hearing LossASPIRIN, FOLIC ACIDIts record names the diseaseClinicalTrials.gov
NCT05403229The Role of Migraine Prophylaxis Agent Topiramate in Treating Patients With Sudden Sensorineural Hearing LossPhase 2140Sudden Deafness, Sudden Sensorineural Hearing LossTOPIRAMATEIts record names the diseaseClinicalTrials.gov
NCT07540728Trans-round Window Membrane Intracochlear SteroidPhase 2108Sudden Hearing LossDEXAMETHASONE, TRIAMCINOLONE ACETONIDEIts record names the diseaseClinicalTrials.gov
NCT05623384Effect of Ultrasound-guided Stellate Ganglion Block Combined With Facial Nerve and Glossopharyngeal Nerve Block on the Treatment of Sudden DeafnessNot applicable90Sudden DeafnessMECOBALAMINOpen Targets' reading of its recordClinicalTrials.gov
NCT06467526Efficacy and Safety of Hydroxychloroquine in the Treatment of Sudden Sensorineural Hearing LossPhase 280Sudden Hearing LossHYDROXYCHLOROQUINE, PREDNISOLONEIts record names the diseaseClinicalTrials.gov
NCT03974867Vestibular Prognosis Assessment of ISSNHL With Vestibular Dysfunction Treated With Oral or Intratympanic GlucocorticoidsNot applicable72Vestibular Vertigo, Sudden Hearing LossMETHYLPREDNISOLONE, PREDNISONEIts record names the diseaseClinicalTrials.gov
NCT04129983Treatment of Sudden Deafness With Prednisone+Hyperbaric Oxygen and Prednisone+Somatosensory StimulationNot applicable60Hearing Loss, Sudden, Prednisone Acetate, Hyperbaric Oxygen, Somatic StimulusPREDNISONEOpen Targets' reading of its recordClinicalTrials.gov
NCT05849519Small Sample,Unicentric,Randomized, Controlled Clinical Study of Coenzyme I for Injection in the Treatment of Sudden Sensorineural Hearing LossEarly phase 136Sudden Sensorineural Hearing LossNADIDEIts record names the diseaseClinicalTrials.gov
NCT01621256Efficacy, Safety, and Tolerability of Ancrod in Patients With Sudden Hearing LossPhase 1/231Hearing Loss, Deafness, Hearing Loss, Sensorineural, Hearing Disorders, Ear DiseasesANCRODIts record names the diseaseClinicalTrials.gov
NCT04129697Intratympanic Steroids for Sudden Hearing LossNot applicable30Dexamethasone or Methylprednisolone; Sudden Hearing Loss; Intratympanic SteroidDEXAMETHASONE, METHYLPREDNISOLONEOpen Targets' reading of its recordClinicalTrials.gov
NCT06707389Autologous Blood Monocyte Vesicles for the Treatment of Sudden DeafnessEarly phase 130Sudden Deafness, Sensorineural Hearing LossMETHYLPREDNISOLONEOpen Targets' reading of its recordClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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